chronic neurodegenerative disease associated with htlv-ii infection. | although human t-cell leukemia virus (htlv) type i is known to cause a number of diseases, there has been no convincing evidence of pathological changes after infection with the related virus, htlv-ii. we have found an endemic focus of htlv-ii infection among members of an american indian population in new mexico, usa. we set out to determine the pathological consequences of htlv-ii infection in this population and identified two sisters (aged 59 and 46 years) with a disease superficially resemb ... | 1992 | 1347339 |
high frequency of human t-cell leukemia-lymphoma virus type ii infection in new mexico blood donors: determination by sequence-specific oligonucleotide hybridization. | the albuquerque branch of the united blood services system was found to have an unusually high blood donor human t-cell leukemia/lymphoma virus (htlv) seroprevalence (0.72 per 1,000). many studies investigating htlv seroprevalence and transmission have assumed that all seropositivity is due to htlv type i (htlv-i); recent data dispute this conclusion. we investigated the high prevalence of htlv seropositivity in new mexico by determining whether htlv-i or htlv-ii is predominant in our donors. us ... | 1990 | 2378978 |
incidence of hairy cell leukemia, mycosis fungoides, and chronic lymphocytic leukemia in first known htlv-ii-endemic population. | unlike human t cell leukemia-lymphoma virus type i (htlv-i), htlv-ii has not been convincingly linked to a malignancy. in the first 10 months of serologic screening for htlv-i/ii among blood donors in new mexico in 1988-1989, htlv-i/ii infection was found in 27 donors. htlv-i/ii infection was present in 1.0%-1.6% of american indian and 0.16%-0.27% of hispanic donors compared with 0.009%-0.06% of non-hispanic white donors. htlv-ii was identified by dna amplification in 12 of 13 samples from india ... | 1991 | 1995717 |