| htlv-i associated myelopathy: an endemic disease of canadian aboriginals of the northwest pacific coast? | human t-cell lymphotropic virus type 1 (htlv-i) is responsible for htlv-i associated myelopathy or tropical spastic paraparesis (ham/tsp) and for adult t-cell leukemia/lymphoma (atll). both diseases have been well described in individuals living in japan, west indies, seychelles islands and columbia where infection with htlv-i is considered endemic and in persons whose descendants originated from these endemic areas. we report here 4 cases of ham/tsp in 4 natives from 4 different tribal groups f ... | 1993 | 8313245 |
| human t-cell lymphotropic virus, type i (htlv-i) reported in british columbia. | | 1995 | 7881380 |
| human t-lymphotropic virus type 1 in coastal natives of british columbia: phylogenetic affinities and possible origins. | human t-lymphotropic virus type 1 (htlv-1) infection has been discovered recently in people of amerindian descent living in coastal areas of british columbia, canada. dna sequencing combined with phylogenetic analysis and restriction fragment length polymorphism (rflp) typing of htlv-1 strains recovered from these british columbia indians (bci) was conducted. sequence-based phylogenetic trees distributed the bci isolates among the japanese subcluster (subcluster b) and the geographically widely ... | 1995 | 7474147 |
| human t-lymphotropic virus type i and ii infections in first nations alcohol and drug treatment centres in british columbia, canada, 1992-2000. | since 1992, prevalence data on htlv-i and ii have been collected as part of an ongoing viral seroprevalence study in clients of six first nations alcohol and drug treatment centres in british columbia, canada. prior studies indicate that the lifetime risk of clinical disease (neurologic or hematologic) resulting from htlv-i infection is low (less than 5%) and htlv-ii to date has not been clearly associated with clinical disease. in 1993, the first cases of htlv-i-associated myelopathy or tropica ... | 2002 | 12078968 |
| htlv type i/ii in british columbia amerindians: a seroprevalence study and sequence characterization of an htlv type iia isolate. | it has been established that the human t cell lymphotropic viruses type i and ii (htlv-i and htlv-ii) are both present in some indigenous peoples of the americas. while htlv-i has been identified in coastal british columbia indians (bcis), htlv-ii has not been previously reported in the bcis or other canadian amerindians. the prevalence of htlv-i and htlv-ii in these populations has not been extensively studied. in this article, we examine a group of bcis from vancouver island who belong to the ... | 2000 | 10875614 |
| htlv-i associated adult t cell leukemia/lymphoma: report of two cases from an amerindian population in coastal northwest british columbia. | epidemiological studies of htlv-i infection have demonstrated the presence of this virus in certain amerindian populations in central and south america. we have recently reported the first evidence of endemic htlv-i infection in north american amerindians from the coastal regions of british columbia, canada. while the predominant htlv-i-associated disease observed in british columbia amerindians is the htlv-i associated neurological disease (htlv-i-associated myelopathy/tropical spastic parapare ... | 1996 | 8642874 |
| insights into origins of human t-cell lymphotropic virus type 1 based on new strains from aboriginal people of canada. | the causes of the worldwide distribution of human t-cell lymphotropic virus type 1 (htlv-1) remain incompletely understood, with competing hypotheses regarding the number and timing of events leading to intercontinental spread on historical and prehistoric timescales. ongoing discovery of this virus in aboriginal populations of asia and the americas has been the main source of evidence for the latter. we conducted molecular phylogenetic and dating analyses for 13 newly reported htlv-1 strains fr ... | 2012 | 22921499 |
| initial management of an outbreak of the htlv-1 virus in nunavut, canada. | htlv-1 is a retrovirus known to be endemic in japan, the caribbean, and parts of africa. htlv-1 infection is rare in canada. the last known cases prior to the present cluster in nunavut occurred in 1993, when three aboriginal patients with neurological symptoms in british columbia were found to be infected with htlv-1. the dept. of health and social services in nunavut became aware of the presence of this virus in the nunavut population in early june, 2005 when an individual infected with htlv-1 ... | 2007 | 17929633 |
| mri contributes to the differentiation between ms and htlv-i associated myelopathy in british columbian coastal natives. | human t-cell lymphotropic virus type i (htlv-i)-associated myelopathy/tropical spastic paraparesis (ham/tsp) in british columbian coastal natives has, to date, been a clinical and laboratory diagnosis. however, magnetic resonance imaging (mri) abnormalities have been well-described in other populations in which ham/tsp is endemic. | 2003 | 12619783 |