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markers of health status in an htlv-i-positive cohort.the health effects of chronic human t-cell lymphotropic virus type i (htlv-i) infection were examined in a cohort of japanese men who had emigrated from okinawa, japan, and had been participants in a prospective study in hawaii since 1965. in the present follow-up study carried out in 1987-1988, various health indicators were measured in the subjects, whose mean age was 72.5 years. participation rates were lower in the htlv-i seropositives than in the seronegatives (46.7% vs. 76.0%) in the > or ...19921488961
declining seroprevalence and transmission of htlv-i in japanese families who immigrated to hawaii.this study examined the seroprevalence and transmission of human t cell lymphotropic virus type i (htlv-i) in japanese families who originated in okinawa, an area in which htlv-i is endemic, and who were currently residing in hawaii, a nonendemic area. among a cohort of japanese men whose sera were collected in hawaii in 1967-1975, those of okinawan ancestry had an htlv-i seroprevalence of 11.4%. this study, conducted in 1987-1988, sampled 142 index subjects from this male cohort and tested them ...19911951296
incidence of antibodies against human immunodeficiency virus, human t-cell lymphotropic virus type 1, hepatitis b virus, hemorrhagic fever with renal syndrome virus and chlamydia in tonga and western samoa.among the populations of tonga and western samoa, serum antibodies against human immunodeficiency virus or hemorrhagic fever with renal syndrome virus were not detected (0/904 and 0/192). no serum samples were considered to be positive for antibody against human t-cell lymphotropic virus type 1 (0/527). hepatitis b antigen and antibody were found in 4% (8/192) and 47% (90/192), respectively. chlamydia trachomatis igg and c. psittaci igg antibodies were detected in 39% (75/192) and 47% (91/192), ...19902126048
serological survey of human t-cell leukaemia virus type i in homosexual men in tahiti. 19892716650
htlv-1, hiv-1, hepatitis b and hepatitis delta in the pacific and south-east asia: a serological survey.blood samples from 13 locations in the pacific and south-east asia were tested for evidence of infection with human t-cell lymphotropic virus type-1 (htlv-1), human immunodeficiency virus (hiv-1), hepatitis b virus (hbv) and hepatitis delta virus (hdv). no samples were positive for antibody to hiv-1. antibodies to htlv-1 were found in samples from five locations, the maximum prevalence being 19%, in vanuatu. serological markers of hbv infection were found in all locations, the maximal prevalence ...19882892692
retrovirus-associated adult t-cell leukemia-lymphoma: an epidemiologic study of five cases among hawaii-born offspring of migrant japanese.adult t-cell leukemia-lymphoma (atll) is a distinct clinicopathologic entity etiologically linked to htlv-i infection. we have identified five cases of retrovirus-associated atll among hawaii-born first generation offspring (nisei) of migrant japanese. four patients were offspring of migrant japanese (issei) who emigrated to hawaii from okinawa, an htlv-i endemic area. the fifth patient was born of parents who emigrated to hawaii from fukushima and miyagi prefectures, htlv-i nonendemic areas. ep ...19892921010
modes of transmission and evidence for viral latency from studies of human t-cell lymphotrophic virus type i in japanese migrant populations in hawaii.human t-cell lymphotrophic virus type i (htlv-i) seroprevalence was 20% among hawaiian japanese migrants (issei) and their offspring (nisei) from okinawa compared to 35% in similarly aged men who were lifetime residents of okinawa. a control group of migrants from a nonendemic area of japan, niigata, had low rates of htlv-i antibodies, suggesting that hawaii per se is not an endemic area for htlv-i. factors that were significantly associated with seropositivity in the okinawa migrant groups were ...19863014518
htlv-i-associated t-cell leukemia in hawaii.adult t-cell leukemia (atl) is a disease found endemic in southern japan and the caribbean basin. the human t-cell leukemia virus i (htlv-i) has been implicated epidemiologically as the causative agent in this disease. this paper describes the identification of this disease in hawaii in a second generation immigrant from southern japan. the disease was initially indolent, then clinically explosive, characterized by cutaneous lesions, leukemic lymphocytes with convoluted nuclei of t-cell phenotyp ...19862877581
a seroepidemiologic survey of human t-cell lymphotropic virus type i in two hawaiian hematologic-oncologic practices.a seroepidemiologic survey for antibodies to the human t-cell lymphotropic virus type i (htlv-i) was carried out in two hawaiian hematologic-oncologic practices. specimens of serum or plasma from 215 donors were assayed using the elisa technique, followed by the western blot technique to confirm antibody specificity to htlv-i. of 214 seropositive donors, 16 (7.5%) were positive. of 172 donors of japanese ancestry, 16 (9.3%) were seropositive; none were white, chinese, filipino, or pacific island ...19892735036
human t-cell lymphotropic virus type i (htlv-i) antibodies in pre-diagnostic serum of patients with familial adult t-cell leukemia/lymphoma (atl).in a study of 7498 american men of japanese ancestry in hawaii, 26 incident cases of leukemia or non-hodgkin's lymphoma were identified after a follow-up period of 19 years. two of the cases, who were brothers, were diagnosed with adult t-cell leukemia/lymphoma (atl). both of these brothers had human t-cell lymphotropic virus type i (htlv-i) antibodies in their stored serum which were obtained 4 and 18 years before diagnosis. none of the 24 patients with other hematologic malignancies or the 26 ...19902373493
seroepidemiological survey of htlv-i infection in french polynesia, cook islands and fiji.different population groups of french polynesia, cook islands and fiji were screened for human t-lymphotropic virus type i (htlv-i) antibodies. among 1487 individuals sampled in french polynesia, twelve were considered western blot (wb) indeterminate and one was considered wb-positive for htlv-i infection. this positive subject originated from france and was a blood donor. out of 196 polynesians of the cook islands, one was wb-indeterminate. among populations sampled in fiji, one of 222 melanesi ...19938405324
identification and phylogenetic characterization of a human t-cell leukaemia virus type i isolate from a native inhabitant (rapa nui) of easter island.human t-cell leukaemia virus type i (htlv-i) is endemic in melanesia, one of the three ethnogeographic regions of the pacific; in the other two regions, polynesia and micronesia, the incidence of the virus is relatively low. in an effort to gain new insights into the prevalence of htlv-i in the pacific region, we did a seroepidemiological survey on easter island, which is located on the eastern edge of polynesia. of 138 subjects surveyed, including 108 rapa nui (the native inhabitants of this is ...199910466796
human t-lymphotropic virus type i (htlv-i) and tropical spastic paraparesis or htlv-i-associated myelopathy in hawaii.tropical spastic paraparesis or human t-lymphotropic virus type i (htlv-i)-associated myelopathy is a degenerative encephalomyelopathy with pyramidal tract dysfunction affecting the lower extremities. it is associated with htlv-i infection and found primarily in the caribbean region and in southwestern japan. five cases of tropical spastic paraparesis (or htlv-i-associated myelopathy) in hawaii are reported. all five patients were born in hawaii; four are women. each of the patients has parents ...19902139754
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