| herpes simplex virus type 2 infection, syphilis, and hepatitis b virus infection in haitian women with human immunodeficiency virus type 1 and human t lymphotropic virus type i infections. the johns hopkins university (jhu)/centre pour le developpement et la santé (cds) hiv study group. | antibodies to herpes simplex virus type 2 (hsv-2), antibodies to hepatitis b virus (hbv) core antigen (anti-hbc), and vdrl antibodies (serologic evidence of syphilis) were evaluated in women known to be infected with human immunodeficiency virus type 1 (hiv-1) (n = 95) or human t lymphotropic virus type i (htlv-i) (n = 45) and controls (n = 89). hiv-1-seropositive women were more likely than controls to have antibodies to hsv-2 (88% vs. 54%; p less than .001), anti-hbc (67% vs. 43%; p = .008), a ... | 1992 | 1321862 |
| anti-hiv antibodies and other serological and immunological parameters among normal haitians in montreal. | a matched-pair, cross-sectional study of lymphocyte and serological parameters associated with acquired immune deficiency syndrome (aids) in 189 randomly chosen, ostensibly healthy adult haitian immigrants residing in montreal matched for sex, age (within 5 years), and neighborhood of residence to 189 non-haitian (caucasian) controls was done in 1983-1984. three years later (1986-1987), 41 of the haitian study subjects and 83 of the non-haitian controls participated in a follow-up study centered ... | 1990 | 2153200 |
| t-cell receptor j beta 1/j beta 2 locus rearrangements in an htlv-1-positive t-cell lymphoma with complex chromosomal aberrations. | we report a case of human t-cell lymphotropic virus type 1 (htlv-1)-infected adult t-cell lymphoma that has multiple chromosomal abnormalities, including the presence of an additional 7q22-36, which contains the locus of the t-cell receptor (tcr) beta chain gene. specific tcr j beta 1/j beta 2 gene rearrangements were detected in both marrow and peripheral blood dna, with evidence of further evolution of the transformed clonal population within the peripheral lymphocytes. to our knowledge, this ... | 1996 | 8638612 |
| nucleotide sequence analysis of isolates of human t-lymphotropic virus type 1 of diverse geographical origins. | nucleotide sequences for long terminal repeat (ltr), gag, the protease gene, and pol of a human t-lymphotropic virus type 1 (htlv-1) isolate of probable caribbean origin (htlv-1ch) and a zairian isolate (htlv-1el) were determined providing complete proviral sequences for these isolates. these sequences were compared with those available from previously analyzed isolates. nucleotide sequence differences of 1.2-3.3% were identified among isolates for which complete genetic information was availabl ... | 1991 | 1760230 |
| induction of cd4+, human t lymphotropic virus type-1-specific cytotoxic t lymphocytes from patients with ham/tsp. recognition of an immunogenic region of the gp46 envelope glycoprotein of human t lymphotropic virus type-1. | although the humoral response to human t lymphotropic virus type-1 (htlv-i) has been well characterized in patients with htlv-i-associated neurologic disease (ham/tsp), little is known about a functional htlv-i-specific human t cell response, such as ctl, in these patients. to define both the phenotype of the responding ctl and the fine specificity of this response, long term t cell lines were generated from two ham/tsp patients who were from two different countries. patient's peripheral blood l ... | 1991 | 1704032 |
| the prevalence of human t-cell lymphotropic virus type 1 in the general population is unknown. | human t-cell lymphotropic virus type 1 prevalence estimates are usually based on serological screening of blood donors, pregnant women, and other selected population groups. previously, data on the global epidemiology of human t-cell lymphotropic virus type 1 infection have been summarized unsystematically and without a focus on general populations. to assess the implications of the virus for healthcare systems it is essential to know its past and present prevalence. the widely cited estimate th ... | 2009 | 19940947 |
| molecular cloning of human t-cell lymphotrophic virus type i-like proviral genome from the peripheral lymphocyte dna of a patient with chronic neurologic disorders. | human t-cell lymphotropic virus type 1 (htlv-i), the etiologic agent of human t-cell leukemia, has recently been shown to be associated with neurologic disorders such as tropical spastic paraparesis, htlv-associated myelopathy, and possibly with multiple sclerosis. in this communication, we have examined one specific case of neurologic disorder that can be classified as multiple sclerosis or tropical spastic paraparesis. the patient suffering from chronic neurologic disorder was found to contain ... | 1988 | 2897123 |
| comparison of enzyme-linked immunosorbent and indirect immunofluorescence assays for the detection of human t-cell lymphotropic virus type-i antibodies in sera from rural haiti. | serum samples were obtained from 340 healthy individuals without evidence of neurologic disease living in rural haiti. sera were screened for antibodies to human t-cell lymphotropic virus type i (htlv-i) using two commercially available enzyme immunoassays (eia) and by an indirect immunofluorescence assay (ifa) using a mixture of uninfected h9 cells and htlv-i-infected mt-2 cells. repeatedly positive samples were confirmed by western blot (wb). results with the two eia systems were concordant an ... | 1992 | 1572136 |