| human t lymphotropic virus type i antibody patterns: evidence of difference by age and risk group. | detection of human t lymphotropic virus type i (htlv-i) antibody was assessed on 368 sera from subjects with different clinical features and from different parts of the world. enzyme-linked immunosorbent assay (elisa) and radioimmunoassay for purified p24 antibodies (p24-ria) used as screening tests agreed in 88.7% of the sera. the results from 247 selected sera were compared with western blot (wb). wb was reactive in sera five to 25 times more dilute than the last positive elisa or p24-ria, but ... | 1988 | 3198937 |
| failure to detect human t-lymphotropic virus antibody in wild-caught new world primates. | we conducted a study to look for a simian counterpart of human t-lymphotropic virus (htlv) in wild-caught monkeys in the republic of panama. serum specimens were obtained from 102 monkeys (ateles fusciceps, n = 75; alouatta villosa, n = 18; and cebus capucinus, n = 9) captured in panama's darien rain forest in 1979-1980. specimens were screened for htlv antibody by enzyme-linked immunosorbent assay, and reactive specimens were further tested by western blot. none of the 102 specimens were seropo ... | 1993 | 8102837 |
| human t-lymphotropic virus type ii among guaymi indians--panama. | human t-lymphotropic virus type 2 (htlv-ii) is one of four retroviruses (i.e., htlv-i, human immunodeficiency virus type 1 [hiv-1], and hiv-2) that are known to infect humans. during 1988, investigators from the gorgas memorial laboratory (gml) and the national institutes of health (nih) tested serum specimens collected during 1978-1987 throughout panama to determine the prevalence of htlv-i infection (1), which is endemic in southern japan and the caribbean basin (2). htlv seropositivity rates ... | 1992 | 1549085 |
| relation between human t-lymphotropic virus type i and neurologic diseases in panama: 1985-1990. | human t-cell lymphotropic virus type i (htlv-i) is endemic in the caribbean basin and in japan. htlv-ii, a closely related virus, is endemic in several groups of native americans, including panamanian guaymi. in panama, a nationwide htlv-i/ii seroprevalence of 1-2% has been reported. we evaluated the frequency of htlv-i/ii infection in patients with neurologic diseases admitted to state tertiary hospitals in panama city between 1985 and 1990. nineteen of 322 patients with eligible diagnoses had ... | 1995 | 7552485 |
| complete nucleotide sequence of an amerindian human t-cell lymphotropic virus type ii (htlv-ii) isolate: identification of a variant htlv-ii subtype b from a guaymi indian. | the complete nucleotide sequence of a human t-cell lymphotropic virus type ii (htlv-ii) isolate from a panamanian guaymi indian was determined and analyzed. when this new viral isolate (htlv-iig12) was compared with prototypic htlv-iimot, the overall nucleotide sequence similarity was 95.4%, while the predicted amino acid sequence similarity was 97.5%. although the overall percentage of nucleotide and amino acid identity with prototypic htlv-iimot (subtype a) was high, htlv-iig12 displayed sever ... | 1993 | 8331724 |
| human t-cell lymphotropic virus type i and neurologic disease in panama, 1985 and 1986. | human t-cell lymphotropic virus type i (htlv-i) causes adult t-cell leukemia and has recently been associated with htlv-associated myelopathy/tropical spastic paraparesis. the htlv-i is endemic throughout the caribbean basin and parts of south america, and htlv-associated myelopathy/tropical spastic paraparesis also seems to be common in this area. this 2-year study, 1985 and 1986, was designed to evaluate the occurrence of htlv-i infection in all newly diagnosed cases of selected neurologic dis ... | 1990 | 2346389 |
| spinocerebellar syndrome in patients infected with human t-lymphotropic virus types i and ii (htlv-i/htlv-ii): report of 3 cases from panama. | cerebellar symptoms at onset are unusual in htlv-i/ii-associated tropical spastic paraparesis (tsp). a prospective study of neurological disorders in panama (1985-1990) revealed 13 patients with tsp and 3 with htlv-i/ii-associated spinocerebellar syndrome (hscs) presenting at onset loss of balance, wide-based stance and gait, truncal instability, and mild leg ataxia (vermian cerebellar syndrome), with absent upper limb dysmetria but with postural tremor, downbeat nystagmus, and dysarthria. in 4- ... | 2000 | 10877159 |
| human t-cell lymphotropic virus type i (htlv-i) seroepidemiology and risk factors in metropolitan panamá. | human t-cell lymphotropic virus type i (htlv-i) infection and associated hematologic malignancies cluster in japan, the caribbean basin, and central africa. the authors believe that this study of htlv-i seroepidemiology in the republic of panamá is the first detailed analytic study of environmental factors pertaining to htlv-i infection in representative tropical populations. the study analyzed observational data concerning housing conditions, family composition, and demographic and behavioral a ... | 1988 | 2893539 |
| human t cell lymphotropic virus infection in guaymi indians from panama. | preliminary studies found that 9% of guaymi indians from bocas del toro province have antibody to human t cell lymphotropic virus (htlv-i/ii). the present study enrolled 317 (21% of the population) guaymi indians from changuinola, the capital of bocas del toro province and 333 (70% of the population) from canquintu, an isolated rural village. demographic information and family relationships were ascertained and subjects were screened for neurologic diseases. serum specimens were screened by an e ... | 1990 | 2240369 |
| human t-cell leukemia virus-i and hematologic malignancies in panama. | serum samples were obtained in a 2-year period (november 1, 1984-december 31, 1986) from 136 panamanian patients with hematologic malignancies identified by a population-based registry designed for studies investigating human t-cell lymphotropic virus (htlv)-i. only three patients had clinical and serologic findings of htlv-i-associated adult t-cell leukemia/lymphoma (atll). the authors conclude that although classical htlv-i-associated atll occurs in the panamanian population, it is not as prev ... | 1989 | 2720568 |
| [neurologic diseases associated with the htlv-1 virus in panama]. | studies of the prevalence of the human t-cell lymphotropic virus (htlv-1) in 1984 to 1986 in the republic of panama revealed a national seroprevalence of 1 to 2%. since 1985 clinical epidemiological studies of neurological diseases associated to htlv-1 are being done. two hundred and fitly six clinical cases of thirty eight different neurological diseases of unknown etiology studied in the neurology services of the santo tomas hospital and the social security metropolitan hospital complex have b ... | 1990 | 2284449 |
| isolation of human t-cell lymphotropic virus type 2 from guaymi indians in panama. | human t-lymphotropic virus type i (htlv-i) is associated with adult t-cell leukemia/lymphoma and with a chronic degenerative myelopathy. however, another major type of htlv, htlv-ii, has been isolated only sporadically, and little is known of disease associations, transmission routes, and risk factors for htlv-ii infection. recent studies indicate that a high percentage of certain groups of i.v. drug users and blood donors are infected with htlv-ii. seroepidemiologic studies have found an elevat ... | 1990 | 2247455 |