| htlv-i in neurological patients from some indian ocean islands. | | 1991 | 2051310 |
| neuroepidemiology of human t-lymphotrophic virus type-i-associated tropical spastic paraparesis. | tropical spastic paraparesis (tsp) is a chronic neurological syndrome of gradual onset involving the pyramidal tracts and upper motor neurons, resulting in weakness and stiffness of the lower extremities, hyperactive tendon reflexes, spasticity, low back pain, and urinary disturbances. clusters of endemic tsp have been noted in africa, the seychelles islands, colombia, and the caribbean. recently, studies have linked human t-lymphotrophic virus type-i (htlv-i) with the endemic form of the diseas ... | 1989 | 2786158 |
| htlv-i associated myelopathy in a seychellois immigrant. | to describe the clinical and laboratory features of human t-lymphotropic virus type i (htlv-i) associated myelopathy in an immigrant from the seychelles. | 1993 | 8316110 |
| common origin of human t-lymphotropic virus type-i from iran, kuwait, israel, and la réunion island. | we found previously that kuwaiti htlv-i isolates had two nucleotide substitutions in the most frequently sequenced regions of htlv-i genome, namely: t-->c 4783 in the pol and t-->c 6569 the env genes. these substitutions were observed rarely in other htlv-i isolates and seemed to be good markers of the htlv-i lineage, the "epicentre" of which was located in mashhad, iran. to test this hypothesis we sequenced the fragments of htlv-i genome including sites 4783 and 6569 from seven isolates obtaine ... | 1997 | 9131461 |
| phylogenetic classification of human t cell leukaemia/lymphoma virus type i genotypes in five major molecular and geographical subtypes. | proviral dna was obtained from ex vivo peripheral blood mononuclear cells of 75 human t cell leukaemia/lymphoma virus type i (htlv-i)-infected individuals who were either asymptomatic or had adult t cell leukaemia or tropical spastic paraparesis/htlv-i-associated myelopathy. amplified long terminal repeats (ltrs) were analysed for restriction fragment length polymorphisms (rflps). the results, together with previously published ltr data (a total of 180 specimens analysed), showed the presence of ... | 1994 | 7996161 |
| seroepidemiology, viral isolation, and molecular characterization of human t cell leukemia/lymphoma virus type i from la réunion island, indian ocean. | data indicate the presence in the seychelles islands of a high level of human t cell leukemia/lymphoma virus type i (htlv-i) endemicity as well as the presence of tropical spastic paraparesis/htlv-i-associated myelopathy (tsp/ham). we present here the results of an hospital survey performed since 1988 in la réunion island, located in the indian ocean southeast of the seychelles archipelago, aimed at evaluating htlv-i endemicity, detecting htlv-i-associated diseases, and characterizing viral isol ... | 1994 | 7915530 |
| the epidemiology of myelopathy associated with human t-lymphotropic virus 1. | a progressive spastic myelopathy is one of the principal manifestations of the human t cell lymphotropic virus type 1. recent research is reviewed on the geography and epidemiology of this specific form of tropical spastic paraparesis. first recognized in the caribbean, colombia and japan, it is now also confirmed as a major neurological problem in areas of eastern brazil, western equatorial africa, natal and seychelles, with other scattered foci world-wide. accurate surveys call for sophisticat ... | 1993 | 7687800 |
| human t-lymphotropic virus type i antibodies in the serum of patients with tropical spastic paraparesis in the seychelles. | tropical spastic paraparesis (tsp), a chronic myelopathy of unknown etiology, was studied in the seychelles. human t-lymphotropic virus type i (htlv-i) and human immunodeficiency virus antibodies were determined using an enzyme-linked immunosorbent assay and confirmed with an indirect fluorescent antibody test in serum samples of 20 patients with tsp and 16 controls. test results indicated that 17 patients (85%) and two controls (transverse myelopathy and clinically probable multiple sclerosis) ... | 1987 | 2883962 |