kolokosides a-d: triterpenoid glycosides from a hawaiian isolate of xylaria sp.four new triterpenoid glycosides, kolokosides a-d (1-4), along with the known compound 19,20-epoxycytochalasin n, were isolated from cultures of a hawaiian wood-decay fungus (xylaria sp.). the structures and relative configurations of 1-4 were determined primarily by analysis of nmr data, and the absolute configuration of 1 was assigned by application of the exciton chirality method. compound 1 exhibited activity against gram-positive bacteria.200717284074
waikialoid a suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic candida albicans.a chemically prolific strain of aspergillus was isolated from a soil sample collected near waikiki beach, honolulu, hawaii. the fungus produced several secondary metabolites, which were purified and placed in our natural products library and were later screened for substances capable of inhibiting biofilm formation by candida albicans. it was determined that one of the secondary metabolites from the hawaiian fungal isolate, a new complex prenylated indole alkaloid named waikialoid a (1), inhibit ...201222400916
solanapyrone analogues from a hawaiian fungicolous fungus.four new solanapyrone analogues (solanapyrones j-m; 1-4) have been isolated from an unidentified fungicolous fungus collected in hawaii. the structures and relative configurations of these compounds were determined by analysis of 1d nmr, 2d nmr, and ms data. solanapyrone j (1) showed antifungal activity against aspergillus flavus and fusarium verticillioides, while both 1 and 2 showed activity against staphylococcus aureus and candida albicans.200717663585
botany, traditional uses, phytochemistry and pharmacology of waltheria indica l. (syn. waltheria americana): a review.waltheria indica l. (syn. waltheria americana) is commonly used in traditional medicine in africa, south america and hawaii, mainly against pain, inflammation, conditions of inflammation, diarrhea, dysentery, conjunctivitis, wounds, abscess, epilepsy, convulsions, anemia, erectile dysfunctions, bladder ailments and asthma. aim of the review to provide an up-to-date overview of the botany, phytochemistry, traditional uses, pharmacological activities and toxicity data of waltheria indica. addition ...201323608240
in vitro survival of human pathogenic fungi in hawaiian beach vitro studies utilizing 4 pathogenic fungi, trichosporon cutaneum, candida albicans, microsporum gypseum and trichophyton mentagrophytes, all known from hawaiian beaches, indicate that they survive in the fluctuating beach habitat where they can serve as potential sources of infection for significant periods of time. survival was measured by testing the viability of propagules at intervals for 6 months. all species survived 6 months under 1 or more experimental conditions. survival patterns s ...1979375438
ethnicity and other possible risk factors for candidemia at 3 tertiary care university hospitals in hawaii.a total of 108 cases of candidemia detected in 3 tertiary care university hospitals in hawaii between january 2001 and december 2002 were retrospectively reviewed. candida albicans, candida glabrata, and candida tropicalis accounted for 28% of the cases. mortality among filipino patients was significantly higher than that among other ethnic groups (71% vs 48%; p<.05).200617080389
Displaying items 1 - 6 of 6