| co-dominance of g1 and emerging g3 rotaviruses in hong kong: a three-year surveillance in three major hospitals. | the world health organization recommends rotavirus vaccines be included in all national immunization programs as part of a strategy to control diarrhoeal diseases. sentinel surveillance is advised to monitor impact post-vaccine introduction and to document changes in genotype distribution. | 2011 | 21330195 |
| norovirus as cause of benign convulsion associated with gastro-enteritis. | rotavirus and norovirus gastro-enteritis (ge) are common in children. complications, except severe dehydration, are rare. rotavirus was known to cause seizures and even ge encephalopathy, but these complications are less described in norovirus infection. the objective of this study is to compare the demographic features, clinical manifestations including the incidence of afebrile seizure, and the outcomes in children with rotavirus and norovirus infections. | 2011 | 21309881 |
| estimates of rotavirus disease burden in hong kong: hospital-based surveillance. | we conducted prospective, hospital-based surveillance for rotavirus disease for a 2-year period at 4 of 12 public government (hospital authority [ha]) hospitals in hong kong. it has been estimated that ha hospitals provide 90% of inpatient care in hong kong. | 2005 | 16088809 |
| hospital-based study of the economic burden associated with rotavirus diarrhea in hong kong. | rotavirus infection is the most common cause of severe diarrhea in both developed and developing countries. | 2005 | 16088808 |
| changing epidemiology of rotavirus g-types circulating in hong kong, china. | group a rotaviruses are the most common cause of severe diarrhoeal disease in young children worldwide. the development of a vaccine is advocated by the world health organization. obtaining local baseline information regarding rotavirus strain variation is important to ensure matching of circulating and vaccine strains. the current study was undertaken to determine the epidemiology of rotavirus g-types in hong kong in anticipation of a vaccination program. from 2001 to 2002 over a period of one ... | 2005 | 15543567 |
| laribacter hongkongensis: a potential cause of infectious diarrhea. | in this study, we describe the isolation of laribacter hongkongensis, a recently described genus and species of bacterium, in pure culture on charcoal cefoperazone deoxycholate agar from the stool of six patients with diarrhea. three patients were residents of hong kong, and three of switzerland. in none of the stool samples obtained from these six patients was salmonella, shigella, enterohemorrhagic escherichia coli, vibrio, aeromonas, plesiomonas, or campylobacter recovered. rotavirus antigen ... | 2003 | 14711474 |
| intussusception trends in hong kong children. | to assess trends in intussusception and to validate the coding in hong kong's computerised discharge information system. | 2007 | 17664532 |
| rotavirus infection in hong kong: epidemiology and estimates of disease burden. | rotavirus gastroenteritis should soon be a vaccine-preventable disease. in a 10-year survey of rotavirus gastroenteritis conducted at the prince of wales hospital (pwh), 2281 cases were detected of which 2213 (97%) occurred in children < 5 years old. a consistent epidemic occurred each winter during the months of december and january. of all laboratory-confirmed cases, 78% were community-acquired with a mean hospital stay of 4.7 days. the estimated incidence of rotavirus-attributed hospitalizati ... | 1998 | 9692611 |
| rotavirus vaccination for hong kong children: an economic evaluation from the hong kong government perspective. | to perform an economic analysis of government-funded universal rotavirus vaccination in hong kong from the government's perspective. | 2008 | 17855438 |
| surveillance of childhood diarrhoeal disease in hong kong, using standardized hospital discharge data. | discharge information for all hong kong government hospitals, which is routinely collected through the clinical management system (cms), was used to assess the relative importance of all causes of diarrhoeal illness and to address the issue of under-diagnosis of rotavirus by linking discharge diagnostic codes with actual laboratory results for one hospital. of all children less than 5 years of age hospitalized in hong kong in the 2-year period july 1997 to june 1999, 12,257 (11%) were discharged ... | 2004 | 15310163 |
| incidence of rotavirus diarrhea and intussusception in hong kong using standardized hospital discharge data. | incidence for rotavirus and intussusception was estimated from standardized discharge data for all hong kong government hospitals (1997 to 1999). intussusception incidence in infants (78 to 100 of 100,000) was relatively high. the distinct winter seasonality of rotavirus was not evident for intussusception. during the first 5 years of life an estimated 1 child of 28 is admitted with rotavirus infection (4% of all medical admissions). | 2002 | 12237607 |
| aetiology of acute diarrhoea in hospitalized children in hong kong. | to determine the role of enteric pathogens in acute childhood diarrhoea in hong kong, 388 children with diarrhoea and 306 children of similar age without diarrhoea were evaluated in a hospital-based study during a one-year period from august 1994 to july 1995. of the diarrhoeal cases, 55% were under 1 year and 95% were below 5 years of age. on admission, 22% had some dehydration but none was severely dehydrated. all children were well nourished. oyer 60% of children with diarrhoea had one or mor ... | 1996 | 8911454 |
| infectious diarrhoea in hong kong. | the role of enteric pathogens in diarrhoeal patients presenting at a large general hospital in hong kong from may 1984 to december 1990 was assessed. a total of 3267 organisms were isolated. the gastroenteric salmonellae were the most common pathogens (45%), followed by rotavirus (34%) and campylobacters (11%). shigellae or vibrios constituted 5% or less of the total isolations. both salmonellae and campylobacters were isolated more often from infants while rotavirus was more common in young chi ... | 1993 | 8459483 |
| rna-electrophoresis as a typing method for nosocomial rotavirus infection in a special-care baby unit. | during january and february 1988 an outbreak of nosocomial rotavirus infection occurred in a special-care baby unit (scbu). seven infants were affected, of whom five had symptoms of diarrhoea. typing by rna electrophoresis (electropherotyping) demonstrated that a single rotavirus strain was responsible for the outbreak. the epidemic electropherotype was introduced by an infant with diarrhoea admitted directly into the scbu from the community. eight other electropherotypes were identified during ... | 1989 | 2567767 |
| use of intravenous fluids in hong kong children hospitalised for diarrhoea and relationship to severity and aetiology. | this study assessed the clinical management and impact of diarrhoea aetiology (rotavirus positive/negative) and rotavirus genotype on diarrhoeal disease severity. of 7391 diarrhoea admissions less than 5 years of age over a 2-year period, 80% of patients were tested for rotavirus, 87% were cultured for bacterial pathogens and 78% were assessed for both. diarrhoeal severity scores were greatest in those children with mixed rotavirus and bacterial infections. between 1.3 and 8.4% of infants were c ... | 2009 | 19931721 |
| prevalence of diarrhea viruses in hospitalized children in hong kong in 2008. | a total of 209 stool samples were collected from pediatric patients admitted for acute gastroenteritis in a hospital in hong kong, during an 8-month period from january to august 2008, and were tested for the presence of rotavirus, norovirus, sapovirus, adenovirus, and astrovirus using a multiplex rt-pcr assay. the most common virus was rotavirus group a (59 of 209, 28%, mainly serotypes g1, g2, g3, and g9), followed by norovirus group ii (48 of 209, 23%), adenovirus (7 of 209, 3%, serotypes 2, ... | 2009 | 19774686 |
| occurrence of rotaviruses in guangzhou and hong kong. | electropherotypes of human rotavirus (hrv) isolated from hong kong and guangzhou were compared to study the transmission of hrv between the cities. forty-one electropherotypes were identified from 418 hospitalized patients with hrv infection at the queen mary hospital, and 22 were detected from 66 outpatients in community clinics at a separate area in hong kong. nineteen electropherotypes were detected in 370 hospitalized cases of hrv infection from seven hospitals in guangzhou. results showed t ... | 1988 | 2826616 |
| nosocomial gastroenteritis in paediatric patients. | between november 1982 and april 1985, 2228 children under the age of 5 years with acute gastroenteritis were admitted to the paediatric isolation ward of queen mary hospital, department of paediatrics, university of hong kong. in 56.2% the causative agent was identified as rotavirus, salmonella, campylobacter, shigella, escherichia coli or a combination of these pathogens. our isolation procedures included cohort nursing of all diarrhoeal patients in two separate rooms (each accommodating 6 pati ... | 1989 | 2575634 |
| escherichia coli associated with childhood diarrheas. | we studied 2,246 episodes of childhood diarrhea over a 2-year period in a general hospital serving a population of about one million on the island of hong kong. rotavirus (24%) and nontyphoid salmonellas (23%) were the most common causal agents, followed by campylobacter sp. (9%). rotavirus occurred largely during winter, whereas salmonellas and campylobacter sp. occurred more commonly during summer and autumn, respectively. enterotoxigenic escherichia coli was rarely isolated (1%), and the isol ... | 1987 | 3320082 |
| molecular epidemiology of human rotavirus infection in children in hong kong. | rotavirus was identified in 256 (28.5%) of 899 hospitalized children with diarrhea during a 12-month period in hong kong. fourteen electropherotypes were identified, and the appearance of each occurred in a sequential manner during the study period. one patient was shown to be mixedly infected with two prevalent electropherotypes. sequential stool specimens from another case showed the appearance of an extra rna band during the course of the diarrheal episode. | 1986 | 3007572 |
| distinct populations of rotaviruses circulating among neonates and older infants. | we obtained three stool specimens from each of 371 neonates. two specimens were obtained between days 1 and 3 after birth, while they were in the hospital, and one specimen was obtained between days 6 and 14 after birth, after they had been discharged from the hospital. seventy neonates excreted human rotavirus (hrv) while they were in the hospital, and the incidence rate for the cohort was 0.094 episodes per infant day. the incidence rate of community-acquired neonatal infections was markedly r ... | 1990 | 2161863 |