| prevalence of hiv-2 infection in a family planning clinic in lisbon. | a significant proportion (10%) of notified aids cases in portugal are due to hiv-2 infection as a result of the close connections of portugal with western african countries (ex-portuguese colonies) where there is a high hiv-2 seroprevalence. we conducted a seroepidemiological study of hiv-1 and hiv-2 infection in 1400 women attending family planning and antenatal clinics in a health centre in lisbon with the objective of analysing whether there was evidence of hiv-2 spread in this population. th ... | 1992 | 1504161 |
| [three years of aids. experience of the curry cabral hospital with hiv infections (1985-1988)]. | the aa. present a retrospective study on their experience with hiv positive patients, followed on the infectious diseases department of the hospital curry cabral, in lisbon. this study was done in 90 patients seen since 1985 till march 1988. from the 90 patients, 81 were hiv--1 positive, 6 hiv--2 and 3 hiv1 + hiv2 positives. it is presented their distribution by sex (male = 97.8%), age (mean--36.5 years), risk groups (homosexuals--64.4%, heterosexuals--21.1%, ivda--7.7%, blood-related--5.6%), an ... | 1989 | 2624155 |
| the karpas aids cell test compared with an enzyme-linked immunosorbent assay for detecting antibody to the human immunodeficiency viruses (hiv-i and hiv-2). | we have compared the karpas aids cell test for antibodies to the human immunodeficiency viruses (hiv) with a commercial enzyme-linked immunosorbent assay (elisa) (organon teknika) by testing serum samples from 324 intravenous drug abusers in turin. the cell test was found to be more sensitive and as specific as the elisa with the serum samples from the drug abusers. in lisbon, 30 samples were tested on slides containing cells infected with hiv-1 and/or hiv-2. all 15 samples, which were positive ... | 1988 | 3294299 |
| outbreak of multiple drug-resistant tuberculosis in lisbon: detection by restriction fragment length polymorphism analysis. | multidrug-resistant tuberculosis (mdr-tb) mainly among human immunodeficiency virus (hiv) seropositive patients in lisbon hospitals in 1996-1997. | 1999 | 10094321 |
| human immunodeficiency virus type 2 (hiv-2) in portugal: clinical spectrum, circulating subtypes, virus isolation, and plasma viral load. | the human immunodeficiency virus type 2 (hiv-2) is responsible for 4. 5% of aids cases in portugal. six hiv-2 subtypes have been described so far, subtype a being proposed as more pathogenic than the rest. the relationship between the clinical status and levels of both cellular and plasma hiv-2 viraemia is not well known, nor their modifications under antiretroviral therapy. thirty-two consecutive hiv-2 infected persons (17 men, 15 women) attending two different hospitals in lisbon in 1997 were ... | 2000 | 10745242 |
| the rise and fall of k65r in a portuguese hiv-1 drug resistance database, despite continuously increasing use of tenofovir. | the overall prevalence of the k65r mutation in hiv-1 reverse transcriptase has increased in treatment-experienced patients, mostly attributed to the increasing use of tenofovir (tdf). a number of tdf-based regimens are associated with high rate of early virological failure. in this study, we evaluated the impact of these combinations on k65r selection over time. | 2009 | 19038365 |
| discordant genotypic interpretation and phenotypic role of protease mutations in hiv-1 subtypes b and g. | hiv-1 group m is classified into nine different subtypes. most antiretroviral (arv) drugs have been developed for subtype b, and the response of non-b subtypes in terms of susceptibility and the acquisition of drug resistance when facing those drugs is largely unknown. in this study, we aimed to address differences in the impact of protease inhibitor (pi)-selected mutations on subtypes b and g. | 2009 | 19136678 |
| sexually transmitted infections and related sociodemographic factors in lisbon's major venereology clinic: a descriptive study of the first 4 months of 2007. | to assess the prevalence of sexually transmitted infections (sti) and relationships between them and sociodemographic/behavioural data in the major venereology clinic in lisbon. | 2010 | 20015172 |
| a new genotype 2 subcluster identified among gbv-c strains circulating in the lisbon metropolitan area of portugal. | the rate of infection by the gbv-c virus was investigated in a group of 214 individuals at high risk of infection with parenterally transmitted viruses, and all living in the lisbon metropolitan area (portugal). rna was extracted from plasma samples, and a fragment of the 5'-utr was amplified by rt-pcr, disclosing a high prevalence of infection (40.7%). most probably due to similar modes of viral transmission, the majority of gbv-c (+) individuals were found to be coinfected with hiv and/or hcv. ... | 2010 | 20087931 |
| hepatitis c virus subtypes circulating among intravenous drug users in lisbon, portugal. | hepatitis c virus (hcv) infects 2-3% of the world population and intravenous drug consumption is the leading cause of transmission in industrialized countries. the unavailability of data on the molecular epidemiology of hcv infection in portugal prompted the study of hcv subtypes circulating among intravenous drug users residing in the lisbon metropolitan area and sampled about 10 years apart (1998-2000 and 2008-2009). partial coding sequences for e1 and/or ns5b were obtained from 124 individual ... | 2011 | 21328374 |
| [prevalence of hiv1 and hiv2 infection in women living in an area of lisboa city]. | a seroprevalence study of hiv1 and hiv2 infection in women attending a family planning and an antenatal clinic was done in an area of the city of lisbon where 7% of the population is of african origin. the protocol of study was of non linked type although with the possibility of collecting a second sample of blood for confirmation of results. epidemiological, social and clinical data were collected from 1390 women and this was followed by the collection of a blood sample for the seroepidemiologi ... | 2002 | 1867118 |
| de novo hiv infection diagnoses in a department of dermatology and venereology in lisbon, portugal. | background portugal has the highest prevalence rate of hiv infection in western europe. the proportion of patients with a late diagnosis, carried out in full-blown aids stage, remains high. skin and mucous membrane manifestations are not rare in these patients. objective a demographic, clinical, and laboratorial characterization of patients with de novo hiv infection diagnosis made in the department of dermatology and venereology of a central hospital in lisbon, portugal. methods retrospective r ... | 2017 | 27815548 |