| characterization of antibody responses to wolbachia surface protein in humans with lymphatic filariasis. | symbiotic wolbachia organisms of filarial nematodes have received much attention as possible chemotherapy targets and disease-causing organisms. in order to further investigate the association between anti-wolbachia immune responses and chronic filarial disease in humans, antibody responses to wolbachia surface protein (wsp) were assayed in serum samples collected from 232 individuals living in leogane, haiti, an area where wuchereria bancrofti infection is endemic, and from 67 north americans w ... | 2003 | 12933853 |
| bancroftian filariasis in haiti: preliminary characterization of the immunological responsiveness of microfilaremic individuals. | patent infections with the lymphatic filariae, wuchereria bancrofti and brugia malayi, are associated with suppressed in vitro cellular responsiveness to filarial antigens. in studies of bancroftian filariasis in haiti, a significant number of microfilaremic individuals can be characterized as "responders" to filarial antigens. cells from 37/74 untreated microfilaremic subjects responded to b. pahangi antigen (stimulation ratio greater than 2) as detected by in vitro blastogenesis. a comparison ... | 1988 | 3277457 |
| multiplex bead assay for serum samples from children in haiti enrolled in a drug study for the treatment of lymphatic filariasis. | abstract. a multiplex bead assay (mba) was used to analyze serum samples collected longitudinally from children enrolled in a drug trial for treatment of filariasis in leogane, haiti. recombinant antigens bm14 and bm33 from brugia malayi, third polar tube protein (ptp3) from encephalitozoon cuniculi, and merozoite surface protein-1(19) (msp-1(19)) from plasmodium falciparum were coupled to carboxylated polystyrene microspheres. igg responses to ptp3 and msp-1(19) were not affected by albendazole ... | 2011 | 21813840 |