| cloning and characterization of a repetitive dna sequence specific for wuchereria bancrofti. | a genomic library constructed in a bacteriophage lambda replacement vector (embl3) with wuchereria bancrofti dna partially digested with sau 3a i was screened with 32p-labeled w. bancrofti total dna, and a strongly reactive recombinant, embl3wb34, was isolated. this clone contained an approximately 16-kb insert that showed some cross-hybridization with brugia malayi and b. pahangi dna. however, a 969-bp subclone from embl3wb34, designated pwb12, hybridized only with w. bancrofti dna and was able ... | 1994 | 7943578 |
| filarial diseases in ceylon: a geographic and historical analysis. | medical records concerning filarial diseases in ceylon date from the account of davy[1], though there are hints as to the more obvious manifestations in the old chronicles of the country, too. a first survey was conducted in 1912/1913 concentrating on urban areas, followed by a second survey in the 1930s with emphasis on the rural parts. the results displayed a remarkable distribution pattern: wuchereria bancrofti, the so-called "urban type", concentrated in galle and matara towns, whereas brugi ... | 1983 | 6152421 |
| entomological aspects of filariasis control in sri lanka. | historical events and suitable environmental conditions in the southwestern coastal areas of sri lanka have led to the establishment of a zone of endemic filariasis caused by wuchereria bancrofti and transmitted by culex pipiens fatigans. the previous brugia malayi foci, scattered over widely dispersed areas of the island, were apparently completely eliminated as a result of control of the mansonia vectors by the destruction of the larval host plants in their swamp habitats. control measures by ... | 1974 | 4619057 |
| a cloned antigen for serological diagnosis of wuchereria bancrofti microfilaremia with daytime blood samples. | by differentially screening an adult brugia malayi cdna library with sera from microfilaremic and amicrofilaremic donors infected with wuchereria bancrofti, we have identified a novel parasite antigen denoted sxp-1. recombinant sxp-1 filarial antigen is preferentially recognized by sera from microfilaremic persons with bancroftian filariasis and from skin snip-positive patients with onchocerciasis. antibodies to sxp-1 are restricted to the igg4 subclass and gradually decline after treatment with ... | 1992 | 1484551 |