| non-toxigenic corynebacterium diphtheriae in a boarding school. | a non-toxigenic strain of corynebacterium diphtheriae var. gravis was isolated from 31 boys during an outbreak of sore throats at a boarding school of 15 staff and 134 pupils. despite the non-toxigenicity of the strain involved, conventional isolation procedures were observed and all boys at the school were treated with antibiotics. restrictions on the school were only relaxed when no further carriers were detected. the rationale of such management of an episode involving a non-toxigenic strain ... | 1975 | 48687 |
| intra-tumour c. parvum therapy in gastric carcinoma; a pilot study. | in a preliminary and toxicological study, eight patients with carcinoma of the stomach were treated by corynebacterium parvum immunotherapy prior to surgical excision. killed c. parvum suspension was injected at multiple sites directly into the tumour mass with the aid of fibre-optic gastroscope at doses of 1.5 mg, 4 mg or 8 mg. each patient received two injections of the same dose with an interval of 14 days. the second injections were made 14 to 18 days prior to surgery. no chemotherapy was ad ... | 1977 | 608548 |
| screening for corynebacterium diphtheriae. | a throat swab from a 9 year old girl with pharyngitis yielded a non-toxigenic strain of corynebacterium diphtheriae var mitis and streptococcus group g. c pseudodiphtheriticum was isolated from the throats of two of her four brothers. in each case the isolate was sent to the reference laboratory before full identification. the growth was found to be mixed for one brother; the other isolate being a toxin producing c diphtheriae var gravis. the child was asymptomatic and the case proves that all c ... | 1992 | 1452782 |
| caseous lymphadenitis in goats in england. | | 1990 | 2270637 |
| a report of the investigation and control measures instituted after the isolation of toxin-producing corynebacterium diphtheriae mitis from a child in leeds. | this report describes the control measures instituted and further investigations undertaken after the isolation of toxin-producing corynebacterium diphtheriae from a throat swab taken routinely from a nine-year-old boy, recently returned from pakistan, who had been admitted to hospital in leeds with hepatitis a infection. four of his siblings were subsequently shown to have identical corynebacterium diphtheriae on throat swabbing, except that in one child the organism did not produce toxin. all ... | 1989 | 2517490 |
| plasmids in group jk coryneform bacteria isolated in a single hospital. | investigation of 39 jk-type coryneform isolates from patients at a single hospital revealed that 23 possessed plasmids, which formed six groups on restriction endonuclease analysis. four of the groups were associated with production of similar bacteriocin-like substances, and shared a minimum of 6.4 kilobase pairs of dna. these plasmids, found in isolates from different patients, provide strong direct evidence that person-to-person transmission of jk bacteria had occurred within the hospital. | 1986 | 3023480 |
| diphtheria presenting in the accident and emergency department. | a case of diphtheria encountered in the accident and emergency department is described. in addition, 38 cases of diphtheria have been analysed, and demonstrate that, although now rare in this country, the disease still exists and its clinical features remain unchanged. it presents almost as often in the accident and emergency department as it does to the general practitioner and remains overwhelmingly a disease of children. diphtheria is still a notifiable disease. the diagnosis must be made cli ... | 1987 | 3107580 |
| intravenous infusion of contaminated dextrose solution: the deveonport incident. | | 1973 | 4127558 |
| diphtheria in the manchester area 1967-1971. | | 1974 | 4140991 |
| carriage of corynebacterium acnes in school children in relation to age and race. | | 1974 | 4279690 |
| species of corynebacterium and pasteurella isolated from diseased salmon, trout and rudd. | | 1967 | 6069150 |
| diphtheria carriers in manchester: simultaneous infection with toxigenic and non-toxigenic mitis strains. | a toxigenic strain of corynebacterium diphtheriae mitis was isolated from a 10-week-old baby with membranous tonsillitis, and over the next 6 months thirty-nine symptom-free carriers of nitrate-positive mitis strains were found. all carriers were cleared by 14 days' treatment with erythromycin, though several relapsed after a 5-day course. four contacts carried both toxigenic and non-toxigenic mitis strains; epidemiological evidence and phage studies suggest that these had a common origin. these ... | 1980 | 6101751 |
| studies on the molecular epidemiology of diphtheria. | dna was extracted from toxigenic and nontoxigenic (tox+ and tox-) diphtheria bacilli isolated during a carrier survey that followed recovery of a tox+ corynebacterium diphtheriae mitis from a baby with membranous tonsillitis. the electrophoretic gel patterns of restriction enzyme digests were indistinguishable from one another. they were, however, readily distinguishable from similar gels of dnas extracted from diphtheria bacilli associated with outbreaks elsewhere. hybridisation of a labelled n ... | 1983 | 6138500 |
| an experience of diphtheria in westminster. | | 1984 | 6424155 |
| corynebacterium ulcerans in humans and cattle in north devon. | a case of corynebacterium ulcerans sore throat in a community that drank raw milk from its own farm led to the discovery of another symptomless human infection. eight cows in the herd were found to be infected and the intermittent pattern of excretion was demonstrated in another cow followed through its lactation. further evidence of milk infected by c. ulcerans was found by examining all raw milk samples submitted to the laboratory. two other human cases were diagnosed in devon during the perio ... | 1984 | 6707468 |
| cutaneous diphtheria in bristol. | | 1994 | 7520805 |
| the return of corynebacterium diphtheriae: the rise of non-toxigenic strains. | with the decline in incidence of diphtheria in europe and the usa, many laboratories no longer routinely culture throat swabs for corynebacterium diphtheriae. however, there is an outbreak of infection with toxigenic strains in russia and most adults do not have protective levels of antibody. non-toxigenic strains are known to cause local disease and lysogenic conversion probably occurs in vivo as well as in vitro. non-toxigenic c. diphtheriae var. gravis, formerly quite rare, has been isolated ... | 1995 | 7560966 |
| diphtheria disaster relief. | | 1995 | 7585198 |
| non-toxigenic corynebacterium diphtheriae var gravis in england. | | 1993 | 8099660 |
| immunity to diphtheria in adults in england. | | 1994 | 8148699 |
| epidemiology and molecular characterisation of toxigenic corynebacterium diphtheriae var mitis from a case of cutaneous diphtheria in manchester. | diphtheria is now an uncommon disease in britain. we describe an imported case of cutaneous diphtheria in a previously immunised adult cause by c. diphtheriae var mitis. the control measures adopted to deal with the index case and two secondary cases so as to limit further spread among household and school contacts are outlined. molecular typing was used to study the mode of spread of the organism among contacts. | 1995 | 8666848 |
| toxigenic corynebacterium diphtheriae acquired in england. | | 1996 | 8754453 |
| identification of is1356, a new insertion sequence, and its association with is402 in epidemic strains of burkholderia cepacia infecting cystic fibrosis patients. | burkholderia cepacia is now recognized as an important opportunistic pathogen in cystic fibrosis (cf) and other compromised patients. epidemicity among cf patients has been attributed to at least one particularly infectious strain (strain et12), and both genetic evidence and anecdotal evidence suggest that this strain, currently endemic in ontario, and those causing an epidemic in the united kingdom, are indeed the same. our study was conducted to determine whether there was any association betw ... | 1996 | 8784555 |
| enhanced surveillance of non-toxigenic corynebacterium diphtheriae infections. | | 1996 | 8821021 |
| misdiagnosis of diphtheria: laboratory errors due to toxigenic control strains of corynebacterium diphtheriae. | | 1997 | 9057340 |
| arcanobacteriosis. an infection with streptococcus-like features. | | 1997 | 9331618 |
| nontoxigenic corynebacterium diphtheriae: an emerging pathogen in england and wales? | confirmed isolates of nontoxigenic corynebacterium diphtheriae in england and wales increased substantially from 1986 to 1994. ribotyping of 121 isolates confirmed in 1995 showed that 90 were of a single strain isolated exclusively from the throat; none had previously been identified in toxigenic strains from u.k. or non-u.k. residents. the upward trend in nontoxigenic c. diphtheriae probably represented increased ascertainment, although dissemination of a particular strain or clone may have bee ... | 2000 | 11076724 |
| report on 31 caseous lymphadenitis infected sheep farms in england and wales. | | 2001 | 11400988 |
| mastoiditis in children. | | 1964 | 14222850 |
| prevalence and associations between bacterial isolates from dry mammary glands of dairy cows. | to assess the prevalence and patterns of bacterial isolates, cultures were made from the dry mammary glands of dairy cows in six commercial dairy herds in the uk. milk samples were taken from all four quarters of 480 cows at drying off and at weekly intervals from 14 days before to seven days after calving. a major mastitis pathogen was isolated from at least one quarter of 220 (45.8 per cent) of the cows and from more than one quarter of 90 (18.8 per cent) of them. during the late dry to calvin ... | 2005 | 15689035 |
| immunogenicity of routine vaccination against diphtheria, tetanus, and haemophilus influenzae type b in asian infants born in the united kingdom. | to determine the immunogenicity of routine vaccination against diphtheria, tetanus, and haemophilus influenzae type b (hib) in asian infants born in the uk, and whether maternal antibody suppression occurs. | 2005 | 15908622 |
| survey of the incidence and aetiology of mastitis on dairy farms in england and wales. | a survey of clinical and subclinical mastitis was carried out on 97 dairy farms in england and wales, selected at random from members of a national milk recording scheme. the farmers were asked to collect aseptic milk samples from five consecutive cases of clinical mastitis and from five quarters with high somatic cell counts using a defined protocol, and they completed a questionnaire that included information on the cows sampled, the herd and the history of mastitis in the herd. the samples we ... | 2007 | 17322356 |
| investigations and control measures following a non-travel-associated case of toxigenic cornyebacterium diphtheriae, london, united kingdom, december 2009-january 2010. | this article reports the investigation and control measures undertaken following the identification of a toxigenic strain of cornyebacterium diphtheriae var gravis, designated ribotype minsk , in a partially vaccinated teenager born in the united kingdom with no recent history of travel or known contact with a case of diphtheria or a carrier. this case highlights the need for ongoing work to improve vaccine uptake rates to ensure children receive all scheduled vaccinations. | 2010 | 20430002 |
| toxigenic corynebacterium ulcerans infection in a veterinary student in london, united kingdom, may 2010. | we report on a case of toxigenic corynebacterium ulcerans infection in a fully immunised veterinary student, investigated in london, united kingdom, in may 2010. there was no ongoing transmission in human contacts. possible animal sources were identified. | 2010 | 20738991 |
| infections with corynebacterium diphtheriae: six years' experience at an inner london teaching hospital. | recently, a preponderance of non-toxigenic strains of corynebacterium diphtheriae has been reported, as has the broadening spectrum of disease caused by these strains. this study presents data on 85 isolates of c. diphtheriae over a six year period (1998-2003). eighty were non-toxigenic isolates from patients with sore throat, and five (one toxigenic) were from cutaneous ulcers in travellers returning from endemic areas. when examined in relation to denominator data provided by the health protec ... | 2005 | 15816203 |
| communicable disease associated with milk and dairy products in england and wales: 1983-1984. | during the period 1983-1984 32 outbreaks of disease (ii in 1983 and 21 in 1984) associated with consumption of milk and dairy products and affecting at least 714 people were reported from england and wales. twenty-seven of the outbreaks were attributed to raw milk, two to contaminated pasteurised milk and one each to cheese, cream and ice-cream. twenty-two were due to salmonellas, seven to campylobacters and one each to staphylococcus aureus, yersinia enterocolitica and streptococcus zooepidemic ... | 1986 | 3722841 |
| corynebacterium haemolyticum infections in cambridgeshire. | in the cambridge area, 143 patients infected with corynebacterium haemolyticum were found during the period may 1967 to december 1974. the pharynx was the commonest site of infection and 100 of the 137 pharyngeal infections were in patients aged between 15 and 25 years. such patients usually had a sore throat; about half of them also had a maculopapular rash. the organism and the clinical features which we have come to regard as typical of this infection are briefly described. | 1977 | 269202 |
| isolation of c. diphtheriae gravis in leeds. | | 1982 | 6821100 |