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surgical implications of sclerosing mediastinitis. a report of six cases and review of the literature.sclerosing mediastinitis is an uncommon disease associated with a multiplicity of clinical syndromes. the cause of this disorder is probably an abnormal fibroproliferative response to an inflammatory stimulus, most commonly a granulomatous infection secondary to histoplasma capsulatum. the pathophysiology of this disease is predicated on the encasement of mediastinal vital organ structures within a dense fibrotic mass. this mass appears to emanate from an invasive chronic inflammatory process ca ...19902404701
the pathology of fungal infection and colonization in patients with cystic fibrosis.we used methenamine silver stains to retrospectively evaluate the prevalence of fungi and their associated inflammatory reactions in 63 patients with cystic fibrosis (cf) autopsied between 1982 and 1987. fungi were detected in 13 patients (21%) who fell into three groups: respiratory tract colonization (five patients); localized infection (five patients); and disseminated infection (three patients). hyphae consistent with aspergillus sp were present in five patients; yeast-like cells and/or pseu ...19892793162
disseminated histoplasmosis in persons infected with human immunodeficiency virus.disseminated histoplasmosis is an aids-defining illness that occurs in about 5% of aids patients residing in histoplasmosis-endemic areas of the united states (the mississippi and ohio river valleys). this disease develops as a result of acute infection and perhaps also as the result of reactivation of latent infection: cases reported from areas such as new york city, where histoplasmosis is not endemic, are most likely due to reactivation of an infection acquired earlier in a histoplasmosis-end ...19958547497
disseminated histoplasmosis in renal allograft recipients.histoplasmosis, an opportunistic fungal infection endemic in the ohio and mississippi river valleys, is caused by a dimorphic fungus histoplasma capsulatum. most infections are asymptomatic or self-limited febrile illness. immunosuppressed renal transplant recipients are susceptible to a disseminated disease. we report 5 cases of disseminated histoplasmosis seen in our institute over a period of 25 years amongst 1074 renal transplant recipients. the duration of immunosuppression prior to the dia ...19968664511
cutaneous disseminated histoplasmosis in aids patients in south florida.histoplasma capsulatum is a dimorphic pathogenic fungus endemic to the mississippi and ohio river valleys. in the immunocompetent it causes a self-limited disease, but in the immunocompromised may lead to disseminated disease (disseminated histoplasmosis (dh)). it is one of the opportunistic infections which defines the acquired immunodeficiency syndrome (aids) and is rarely encountered outside endemic regions.19979329891
histoplasmosis in a state where it is not known to be endemic--montana, 2012-2013.histoplasmosis is caused by infection with the dimorphic fungus, histoplasma capsulatum, following inhalation of contaminated soil. among symptomatic patients, the most common clinical presentation is acute pneumonia. persons with compromised immune systems are at risk for disseminated histoplasmosis, a severe illness requiring antifungal therapy that is often characterized by fever, malaise, anorexia, and weight loss. h. capsulatum is endemic in the ohio river and mississippi river valleys, whe ...201324153314
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