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orally administered colistin leads to colistin-resistant intestinal flora and fails to prevent faecal colonisation with extended-spectrum β-lactamase-producing enterobacteria in hospitalised newborns.colonisation and infection with extended-spectrum β-lactamase-producing enterobacteriaceae (esbl-e) is an emerging problem. the aim of this study was to investigate whether colistin, which is reported to be effective against multiresistant enterobacteria, prevents esbl-e colonisation in neonates. for prophylaxis of necrotising enterocolitis, oral gentamicin (15 mg/kg/day) is routinely used in all neonates hospitalised at the neonatal intensive care unit of university hospital graz (austria). dur ...201021074372
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