Publications

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screening of children for enteric bacterial pathogens in the outborn neonatal ward in lagos, nigeria.babies, on admission into a neonatal ward at the lagos university teaching hospital, had their rectal swab specimens examined bacteriologically and screened for enteric bacterial pathogens over a one-year-period at two-week intervals. it was found that on the average there were 3 (9.68%) enteric bacterial pathogens out of an average of 31 admissions at each screening period. the enteric bacterial pathogens isolated included: non-typhoid salmonellae, which accounted for 55 (80.88%) isolates out o ...19911915794
endotoxic activity and enterotoxigenicity of human strains of campylobacter jejuni isolated from patients in a nigerian hospital.limulus gelation assay and dermal schwartzman reaction provided a sensitive and reproducible means of testing the endotoxic activity of hospital strains of campylobacter jejuni in lagos, nigeria. all the 22 isolates of campylobacter jejuni tested for the limulus gelation assay were positive for the production of endotoxin. furthermore, the campylobacter suspensions caused a positive dermal schwartzman reaction in rabbits. the area of skin reaction was less extensive than that produced by escheri ...19892632005
characterization and antibiotic sensitivity of campylobacter jejuni and campylobacter coli isolated from children at the lagos university teaching hospital (luth), lagos, nigeria.one hundred and thirteen rectal swabs and 87 faecal samples obtained from the paediatric casualty of the lagos university teaching hospital, lagos, nigeria were processed for campylobacter jejuni/coli. twenty-two (11%) of the specimens were positive for c. jejuni. biotyping results showed that nine (41%) and eight (36%) belonged to c. jejuni biotypes i and ii respectively, while three (14%) and two (9%) belonged to c. coli biotypes i and ii. serotyping results revealed that c. jejuni biotypes i ...19892651685
campylobacter jejuni antibody in patients with diarrhoea and asymptomatic individuals in lagos, nigeria.seventy patients with acute diarrhoea and sixty asymptomatic children in lagos, nigeria were screened for complement fixing and agglutinating antibodies to campylobacter jejuni in wells of microtitre plates using automatic microtitre pipettes. out of the seventy patients with acute diarrhoea, 55 (78.6%) had complement fixing antibody, while 48 (68.5%) had agglutinating antibody in their sera. twenty-nine (48.3%) and 21 (35%) out of the sixty asymptomatic children screened had complement fixing a ...19892743910
natural bactericidal activity of human serum against strains of campylobacter jejuni isolated in lagos, nigeria.the sensitivity of campylobacter jejuni strains la4, la12, la36, la53, la1214, la1308 and la1309 constituting the most prevalent strains of c. jejuni isolated in lagos, nigeria to the bactericidal activity of normal human serum was determined using microtiter technique. results obtained shows that only strains la 36 and la53 were serum resistant while others (strains la4, la12, la1214, la1308 and la1309) were serum sensitive. this finding is important epidemiologically and is the first report on ...19892805054
production of antisera against campylobacter species in lagos, nigeria. 19883248311
biotypes and serotypes among campylobacter jejuni strains in lagos. 19863568121
gastroenteritis due to campylobacter jejuni in lagos, nigeria. 19854016913
local pattern of acute enteric bacterial infections in man--lagos, nigeria.stool specimen from 994 patients with acute diarrhoeal diseases were processed for bacterial agents known to be responsible for acute diarrhoea. these were from patients seen at the lagos university teaching hospital over a 9 month period. the pattern that emerged showed shigella isolates made up by 36 flexneri; 29 boydii, 21 dysenteriae and 4 sonnei; salmonella isolates were typhi 3, typhimurium 12, enteritidis 3, oranienburg 9, others 8; yersinia enterocolitica 14; campylobacter species 20; en ...19836347763
the changing patterns of campylobacter jejuni/coli in lagos, nigeria after ten years.one hundred and forty-five stool samples from children with diarrhoea at various health centres in lagos were investigated for campylobacter jejuni/coli. these organisms were isolated from 24 samples (16.5%). they were later biotyped as 23 c. jejuni and one c. coli. previous studies (3,6) recorded isolation rates of 5.2% and 11% respectively. no campylobacter species was isolated from 100 control patients who did not have diarrhoea. diarrhoea due to campylobacter jejuni/coli is still common in m ...19947828496
biotyping of campylobacter strains isolated in lagos, nigeria using the modified preston biotype.fifty-eight compylobacter strains were isolated from children with diarrhoea at various health centres in lagos and from healthy chicken. twenty-nine strains of campylobacter were isolated from humans, while the same number were isolated from chicken. the strains were biotyped using the modified preston biotype scheme. the preston biotyping results have been compared with the results of penner serotyping. out of fifty-eight strains studied, the technique identified ten strains (17%) as c. coli, ...19979167277
enteric bacterial pathogens in stools of residents of urban and rural regions in nigeria: a comparison of patients with and without diarrhoea and controls without diarrhoea.a total of 2,400 stool samples comprising 1,200 from patients with diarrhoea (600 each from urban and rural area) and 1,200 similarly divided controls were obtained from school children and clinic attendants of government and private clinics around three designated study centres of edo, lagos and cross river states, nigeria. these were screened for the prevalence of bacteria that could cause diarrhoea. diarrhoea cases in urban areas had a high prevalence rate for campylobacter spp. (28%), follow ...19979661320
distributional patterns of bacterial diarrhoeagenic agents and antibiograms of isolates from diarrhoeaic and non-diarrhoeaic patients in urban and rural areas of nigeria.to determine the prevalence of bacteria that could cause diarrhoea in stool specimens of individuals with and without diarrhoea in both urban and rural areas of nigeria. to ascertain the antibiotic susceptibilities of the bacterial diarrhoeagenic agents isolated. to document the predominant signs and symptoms associated with the various bacterial agents of diarrhoea.199810101427
occurrence of campylobacter species in poultry forms in lagos area of nigeria.samples of poultry droppings were collected from fifty poultry farms in lagos area of nigeria. campylobacter species were isolated from serially diluted samples using bolton selective enrichment medium under microaerophilic condition at 42 degrees c. samples of water, both treated and untreated used in the farms were also analysed in the same manner. fifteen campylobacter strains were isolated from the droppings. all the strains were identified using biochemical characteristics differentiating c ...200516334275
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