| sequence variation and physical state of human papillomavirus type 16 cervical cancer isolates from australia and new caledonia. | sequence diversity over 2600 nucleotides of the upstream regulatory region (urr) and the e6 and e2/e4 genes of 34 human papillomavirus (hpv)16 cervical cancer isolates from australia and new caledonia was investigated. one 81 base duplication, 41 single base substitutions and 1 single base insertion were identified in the urrs. some of these changes are reported here for the first time. several of the 19 changes impacting transcription factor binding sites had the potential to alter promoter act ... | 2002 | 11857370 |