| growing antimicrobial resistance of shigella isolates. | appropriate antibiotic treatment of shigellosis depends on identifying resistance patterns. by studying shigella isolates in central israel from 1998 to 2000, and comparing with the period 1991-1992, we identified a significantly increased resistance to tetracycline (from 23% to 87%, p < 0.00001), high resistance to trimethoprim-sulfamethoxazole (94%) and ampicillin (85%) and emerging resistance to quinolones (0.5-2%). these data mandate local monitoring of resistance and its consideration in em ... | 2003 | 12562716 |