| [haemophilus influenzae type b: epidemiological situation in the state of minas gerais, brazil, 1993-1997]. | among haemophilus influenzae type b (hib) invasive diseases, pneumonia and meningitis are the most relevant in public health due to their frequency and severity. from 1993 to 1997, there were 720 cases of hib meningitis in minas gerais state, brazil, representing the most frequent cause of bacterial meningitis in infants (< 1 year) and the second most frequent among all causes of meningitis. the total estimated cases of invasive hib diseases thus appear to justify the recent inclusion of the vac ... | 2003 | 14666208 |
| effectiveness of haemophilus influenzae b conjugate vaccine on childhood pneumonia: a case-control study in brazil. | the conjugate haemophilus influenzae type b (hib) vaccine has been highly efficacious in reducing type b h. influenzae meningitis. however, information is limited about its impact on childhood pneumonia after vaccine introduction into the routine programme. this study evaluated the effectiveness of hib conjugate vaccine in the reduction of community-acquired pneumonia among infants in central brazil. | 2004 | 15075166 |
| poor clinical outcome for meningitis caused by haemophilus influenzae serotype a strains containing the is1016-bexa deletion. | since the introduction of haemophilus influenzae type b (hib) conjugate vaccines, meningitis caused by serotypes other than hib has gained in importance. we conducted active hospital-based surveillance for meningitis over an 11-year period in salvador, brazil. h. influenzae isolates were serotyped and analyzed by polymerase chain reaction, pulsed-field gel electrophoresis, and dna sequencing to identify strains with a specific deletion (is1016) in the bexa gene (is1016-bexa). we identified 43 me ... | 2010 | 20932170 |