| hantavirus pulmonary syndrome: the four corners disease. | to review the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of hantavirus infections, focusing on the recent outbreak of hantavirus pulmonary syndrome in the us. | 1995 | 7711347 |
| recognition of hantavirus infection in the rural setting: report of first colorado resident to survive. | since may 1993, there has been an outbreak of an acute illness with nonspecific symptoms and signs that rapidly progresses to death. the majority of the cases identified have occurred in the rural southwestern united states, predominantly in the four-corners area comprising new mexico, arizona, utah, and colorado. findings of preliminary investigation by the centers for disease control and prevention suggest that the etiologic agent is a previously unidentified strain of hantavirus. in reported ... | 1993 | 8117354 |
| were four corners victims biowar casualties? | | 1993 | 8235553 |
| update: hantavirus disease--southwestern united states, 1993. | since may 1993, the state health departments in arizona, colorado, new mexico, and utah; the indian health service; and cdc, with the assistance of the navajo nation division of health, have been investigating an outbreak of acute respiratory illness related to a newly recognized hantavirus (1-5). this report updates the investigation and presents information on a recent case of hantavirus-associated respiratory disease in a resident of nevada. | 1993 | 8332114 |
| outbreak of acute illness--southwestern united states, 1993. | beginning in may 1993, cases of acute illness characterized by fever, myalgias, headache, and cough, followed by rapid development of respiratory failure, have been reported to the new mexico department of health (nmdoh), arizona department of health services (adhs), colorado department of health (cdh), and utah department of health (udh). this report presents preliminary findings from an ongoing investigation of this problem, which suggest this illness is associated with a previously unrecogniz ... | 1993 | 8502213 |
| update: outbreak of hantavirus infection--southwestern united states, 1993. | since may 1993, the new mexico department of health, the arizona department of health services, the colorado department of health, the utah department of health, the indian health service (ihs), and cdc, with the assistance of the navajo nation division of health, have been investigating an outbreak of acute illness characterized by a prodrome most commonly including fever, myalgias, headache, and cough, followed rapidly by respiratory failure. preliminary laboratory findings have suggested this ... | 1993 | 8502218 |
| update: outbreak of hantavirus infection--southwestern united states, 1993. | since may 1993, the new mexico department of health, the arizona department of health, the colorado department of health, the utah department of health, the indian health service, and cdc, with the assistance of the navajo nation division of health, have been investigating an outbreak of illness associated with hantavirus infection. this report updates information regarding the relation between illness and infection with a previously unrecognized hantavirus. | 1993 | 8510634 |
| update: outbreak of hantavirus infection--southwestern united states, 1993. | an outbreak of illness associated with hantavirus infection continues to be investigated by state health departments in new mexico, arizona, colorado, and utah; the indian health service; and cdc, with the assistance of the navajo nation division of health. this report updates information regarding the outbreak and presents information on two cases that occurred in the 10 months preceding this outbreak. | 1993 | 8510636 |
| utility of emergency, telephone-based national surveillance for hantavirus pulmonary syndrome. hantavirus task force. | on may 27, 1993, in response to the outbreak investigation of newly recognized hantavirus pulmonary syndrome (hps) in the four corners states (new mexico, arizona, utah, and colorado), the centers for disease control and prevention established a national surveillance case definition for severe, unexplained respiratory disease to determine the extent of hps throughout the united states. a toll-free telephone hotline number was instituted to provide updated information about unexplained respirator ... | 1996 | 8569020 |
| acute infection with sin nombre hantavirus without pulmonary edema. | acute infection with sin nombre virus has been associated with development of hantavirus cardiopulmonary syndrome (hcps), a severe cardiopulmonary illness with respiratory failure and shock. we present two cases of sin nombre hantavirus infections that did not lead to marked pulmonary complications in two otherwise healthy young adults from utah and california. sin nombre virus causes a wider spectrum of disease severity than has been previously reported. | 1999 | 10530462 |
| outbreak of hantavirus infection in the four corners region of the united states in the wake of the 1997-1998 el nino-southern oscillation. | hantavirus cardiopulmonary syndrome (hcps), a rodent-borne zoonosis, has been endemic in the americas for at least several decades. it is hypothesized that the 1991-1992 el niño-southern oscillation (enso) caused increased precipitation that allowed an increase in rodent population densities, thereby increasing the possibility of transmission to humans. the result was a 1993-1994 outbreak of the disease in the four corners states of the southwestern united states. a second strong enso occurred i ... | 2000 | 10823755 |
| state-by-state incidences of hantavirus pulmonary syndrome in the united states, 1993-2004. | we investigated geographic disparity in numbers of hantavirus pulmonary syndrome (hps) cases in the united states. the 12-year incidences of hps (cases/100,000 for total and rural residents) by state did not parallel the number of cases per state. the state with the greatest overall incidence was new mexico, with montana ranking second. when rural incidence based on rural human population sizes were compared, new mexico also had the highest incidence, but utah, nevada, montana, arizona, and colo ... | 2005 | 16011436 |
| changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice. | we examined the impact of season and habitat on sin nombre virus (snv) seroprevalence in deer mice (peromyscus maniculatus) in utah's great basin desert from may 2002 through summer 2003. low mouse captures in 2002 limited analysis for that year. in two seasons during 2003, mouse density and sagebrush cover were positively linked (spring: r = 0.8, p = 0.01; summer: r = 0.8, p = 0.04). in the spring, seroprevalence was negatively correlated with density (r = -0.9, p< 0.01); male and female antibo ... | 2006 | 17255449 |
| differential regulation of pathogens: the role of habitat disturbance in predicting prevalence of sin nombre virus. | deer mice (peromyscus maniculatus) are the primary reservoir for sin nombre virus (snv), a north american hantavirus that causes disease with high mortality in humans. recent studies have proposed that habitat disturbance affects prevalence of snv in deer mice; however, the outcomes proposed in these studies are in opposition to each other. our objectives were to test these divergent hypotheses by: (1) measuring snv infection in deer mice within a patchwork of disturbance; and (2) evaluating the ... | 2008 | 18064494 |
| seasonal variation in sin nombre virus infections in deer mice: preliminary results. | the proportion of deer mice (peromyscus maniculatus) with recently acquired sin nombre virus (snv) infections is an indicator of epizootic intensity and may be key in predicting outbreaks of hantavirus cardio-pulmonary syndrome in humans. we investigated whether incidence of recent infections was related to season, sex, reproductive status, or habitat disturbance. in may and september, 2006, we sampled 912 deer mice at six sites in utah. we determined snv antibody prevalence and estimated the nu ... | 2009 | 19395752 |
| testing mechanisms of the dilution effect: deer mice encounter rates, sin nombre virus prevalence and species diversity. | species diversity has been shown to decrease prevalence of disease in a variety of host-pathogen systems, in a phenomenon termed the dilution effect. several mechanisms have been proposed by which diversity may decrease prevalence, though few have been tested in natural host-pathogen systems. we investigated the mechanisms by which diversity influenced the prevalence of sin nombre virus (snv), a directly transmitted virus in deer mice (peromyscus maniculatus). we monitored both intra and intersp ... | 2009 | 19495881 |
| long-term patterns of immune investment by wild deer mice infected with sin nombre virus. | immunocompetence of animals fluctuates seasonally, however, there is little consensus on the cause of these fluctuations. some studies have suggested that these patterns are influenced by changes in reproductive condition, whereas others have suggested that differences result from seasonal variations in energy expenditures. the objective of our study was to examine these contrasting views of immunity by evaluating seasonal patterns of immune response and reproduction in wild populations of deer ... | 2010 | 20695811 |