| actinomycetoma in the united states. | actinomycetoma (madura foot) caused by actinomadura madurae occurred in an indiana factory worker. previous cases of culture-proven actinomycetoma from the united states and reports of drug therapy were reviewed. treatment with sulfonamides, streptomycin, dapsone, and other antimicrobial agents has been effective. trimethoprim-sulfamethoxazole (tmp-smz) therapy was effective in our case, but sulfadiazine was not. in vitro, smz was 16 times more active against the infecting strain of a. madurae t ... | 1981 | 6979082 |