Publications

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circovirus-like particles in the bursae of young racing pigeons. 19968677611
spatiotemporal patterns and risks of herd breakdowns in pigs with postweaning multisystemic wasting syndrome.a retrospective cohort study of 116 british pig farms was undertaken to investigate the epidemiological risk factors associated with herd breakdowns with postweaning multisystemic wasting syndrome (pmws). farmers reported the pmws status of their herd (case definition 1) and, where applicable, when the disease was first suspected and what they observed; they described a prolonged increase in mortality in six to 16-week-old pigs that was not attributable to any disease known to be on their farm. ...200717545645
assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level.post-weaning multi-systemic wasting syndrome (pmws) causes major economic losses for the english pig industry and severity of clinical signs and economic impact vary considerably between affected farms. we present here a novel approach to quantify severity of pmws based on morbidity and mortality data and presence of porcine circovirus type 2 (pcv2). in 2008-2009, 147 pig farms across england, non-vaccinating for pcv2, were enrolled in a cross-sectional study. factor analysis was used to generat ...201021036410
detection and genetic typing of type 2 porcine circoviruses in archived pig tissues from the uk.porcine circovirus 2 (pcv-2) is implicated as the causative agent of post-weaning multisystemic wasting syndrome (pmws) and is also associated with porcine dermatitis and nephropathy syndrome (pdns). the recent emergence of epidemic pmws in the united kingdom was predated by sporadic cases of pdns dating back to the early 1980's. the aim of this study was to investigate whether pcv-2 dna was present in archival tissues, and if so, to investigate the relatedness of these viruses with contemporary ...200415168203
farm level risk factors associated with severity of post-weaning multi-systemic wasting syndrome.a cross-sectional study involving 147 pig farms across england was conducted in 2008-2009. farm severity of post-weaning multi-systemic wasting syndrome (pmws) was estimated through the use of an algorithm that combined data on post-weaning mortality, pmws morbidity and proportion of porcine circovirus type 2 pcr positive pigs. farms were classified as non/slightly, moderately or highly affected by pmws. data on potential pmws risk factors were collected through interviews, on-farm assessment an ...201121741715
house fly vector for porcine circovirus 2b on commercial pig farms.we investigated the on-farm potential of common farm invertebrates to transmit porcine circovirus genotype 2 (pcv2) and other non-enveloped viruses. in 2007 (pre-pcv2 vaccination) and 2008 (post-pcv2 vaccination), invertebrate communities were trap-collected (8 trap-dates per year), counted and sorted into genus and species groups on 5 farm study sites within england. total dna was extracted from feces of representational cross-sections of pigs on each farm in each year and also from intact samp ...201021145672
a cohort study of post-weaning multisystemic wasting syndrome and pcv2 in 178 pigs from birth to 14 weeks on a single farm in england.our hypothesis was that pigs that develop post-weaning multisystemic wasting syndrome (pmws) are detectable from an early age with signs of weight loss and other clinical and serological abnormalities. therefore, the objective of this study was to investigate the temporally varying and fixed events linked with the clinical incidence of pmws by comparing affected and unaffected pigs in a cohort of 178 male piglets. piglets were enrolled at birth and examined each week. samples of blood were colle ...201020801534
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