| genotype-specific in vitro amplification of sequences of the wild type 3 polioviruses from mexico and guatemala. | the extensive nucleotide sequence heterogeneity among independent genotypes of wild polioviruses permits the systematic design of genotype-specific molecular reagents. we have prepared two sets of polymerase chain reaction (pcr) primer pairs specific for the genotype of wild poliovirus type 3 recently endemic to mexico and guatemala. nucleotide sequences of a representative wild type 3 virus isolated in mexico in 1989 differed from the corresponding sabin 3 (leon 12 a1b) sequences at 167 of 900 ... | 1992 | 1329370 |