| geographical distribution of variant cjd in the uk (excluding northern ireland). | the agent that causes variant creutzfeldt-jakob disease (variant cjd) is indistinguishable from the causative agent of bovine spongiform encephalopathy (bse). the transmission route by which human beings are infected has not been established. one hypothesis is that cases of variant cjd have resulted from exposure to the bse agent via rendering plants involved in the production of meat and bone meal, the main vehicle of the bse epidemic. | 1999 | 10023945 |
| deaths from variant creutzfeldt-jakob disease in the uk. | in 2002, 17 people died from variant cjd (vcjd) in the uk, compared with 20 in 2001 and 28 in 2000. we analysed data for deaths from vcjd since 1995 and estimated the underlying trend in mortality. the trend had a quadratic component (p=0.005), suggesting that the increase was not exponential, and that the previously increasing trend is slowing down. the death rate peaked in 2000. these findings are encouraging, but mortality might increase again in the future. | 2003 | 12620741 |
| the transmission dynamics of bse and vcjd. | the bovine spongiform encephalopathy (bse) epidemic in cattle has had a huge economic impact on the agricultural industries across europe. furthermore, scientific evidence now strongly supporting a link between a new variant of creutzfeldt-jakob disease (vcjd) and consumption of bse-infected animals has further heightened the need both to understand the transmission of these new diseases and to improve control measures to protect public health. in this paper we review work undertaken by our grou ... | 2002 | 11862621 |