efficacy of macrolides vs. metronidazole against entamoeba histolytica clinical isolates. | current treatment of entamoeba histolytica infection requires the use of several agents that are effective at different sites of the body. commonly administered agents such as nitroimidazoles have a high rate of gastrointestinal side effects and their use is restricted during pregnancy. in order to offer new choices, four macrolide antibiotics (erythromycin, clarithromycin, azithromycin, josamycin) and metronidazole were tested for their in vitro activity against e. histolytica. ten clinically i ... | 2001 | 11571837 |