| natural transmission of keystone virus to sentinel rabbits on the delmarva peninsula. | domestic rabbits were exposed in the pocomoke cypress swamp from early may through october 1973, to act as sentinel indicators of keystone (key) virus transmission on the delaware-maryland-virginia (delmarva) peninsula. rabbits were bled weekly and their sera were tested for the presence of neutralizing antibody to both key and james-town canyon (jc) viruses. adult mosquito activity was monitored concurrently by cdc miniature light traps with dry ice. of 100 rabbits exposed, 20 rabbits acquired ... | 1978 | 717629 |
| serologic evidence of jamestown canyon and keystone virus infection in vertebrates of the delmarva peninsula. | serological data accumulated during the past decade indicated that a variety of feral and domestic animals of the delaware-maryland-virginia (delmarva) peninsula were infected with jamestown canyon (jc) and/or keystone (key) viruses (bunyaviridae, california serogroup). neutralizing (n) antibody to jc virus was most prevalent in white-tailed deer, sika deer, cottontail rabbits and horses. key virus n antibody was detected most frequently in gray squirrels and domestic goats. n antibody indicativ ... | 1982 | 7149110 |
| serum antibodies to jc virus, bk virus, simian virus 40, and the risk of incident adult astrocytic brain tumors. | genomic sequences of the human polyomaviruses, jc virus (jcv) and bk virus (bkv), and simian virus 40 (sv40) have been reported from several types of human brain tumors, but there have been no population-based seroepidemiologic studies to evaluate the association between polyomavirus infection and brain tumors. we conducted a case-control study, nested within a prospective cohort, to investigate the association between antibodies to jcv, bkv, and sv40, as measured in serum collected 1-22 years b ... | 2003 | 12750243 |
| markers of past infection with simian virus 40 (sv40) and risk of incident non-hodgkin lymphoma in a maryland cohort. | simian virus 40 (sv40) genome sequences have been detected in human non-hodgkin lymphoma (nhl) tissues, and past infection with sv40 may be a risk factor for nhl. we conducted a population-based nested case-control study to investigate the association between serum antibodies to sv40 and incident nhl. two research serum banks were established in washington county, md, with >45,000 volunteers contributing blood samples collected in 1974 and 1989. incident cases of nhl diagnosed through 2002 (n = ... | 2005 | 15941954 |
| experimental infection of vertebrates of the pocomoke cypress swamp, maryland with keystone and jamestown canyon viruses. | experimental studies were conducted to assess the susceptibility of white-tailed deer (odocoileus virginianus), gray squirrels (sciurus carolinensis), and cottontail rabbits (sylvilagus floridanus) to jamestown canyon (jc) and/or keystone (key) virus infection. viremia occurred in 5 of 6 deer inoculated with jc virus; however, all deer developed key virus neutralizing antibody. based on the observation that antibody elicited by primary infection of deer with either key or jc virus exhibited part ... | 1979 | 453437 |
| prospective study of jc virus seroreactivity and the development of colorectal cancers and adenomas. | infection with jc virus has been proposed as a risk factor for colorectal cancer. a nested case-control study was conducted to evaluate the association between prediagnostic jc virus antibodies and the risk of incident colorectal cancer and adenomas. | 2009 | 19383887 |
| jc virus type 2b is found more frequently in brain tissue of progressive multifocal leukoencephalopathy patients than in urine from controls. | previous studies have shown that strains of human polyomavirus jc (jcv) of asian origin (type 2) are much more highly represented in progressive multifocal leukoencephalopathy (pml) brain than would be expected from their frequency of excretion in urine samples of a comparable control group. the present studies were designed to test whether one subtype of type 2 was preferentially elevated. | 1998 | 10195243 |