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four geographically distinct genotypes of jc virus are prevalent in china and mongolia: implications for the racial composition of modern china.jc polyomavirus (jcv) is ubiquitous in humans, persisting in renal tissue and excreting progeny in urine. it has been shown that the genotyping of urinary jcv offers a novel means of tracing human migrations. this approach was used to elucidate the racial composition of modern china. jcv isolates in the old world were previously classified into nine distinct genotypes. one of them (b1) has a wide domain, encompassing part of europe and the entirety of asia. by constructing a neighbour-joining ph ...19989780057
chinese strains (type 7) of jc virus are afro-asiatic in origin but are phylogenetically distinct from the mongolian and indian strains (type 2d) and the korean and japanese strains (type 2a).we have further characterized the asian genotypes (types 2 and 7) and subtypes of jc virus (jcv). urine samples from 224 individuals with han and mongolian populations were collected in five regions in eastern china: kunming, chengdu, shenyang, chifeng, and manzhouli. also, 99 urine samples were collected from coastal and hill groups in kerala, southern india, and 23 urine samples from seoul, korea. pcr products of four typing fragments were sequenced, including two in the vp1 gene, as well as o ...200415170260
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