| jc virus genotypes in a taiwan aboriginal tribe (bunun): implications for its population history. | the origin of taiwanese aborigines remains obscure; it has been speculated that they may be from either mainland china or southeastern asia. we used the jcv genotyping method to elucidate the origin of bunun aborigines who now live in central mountain areas of taiwan. we found that bunun aborigines carried two major (b1-a2 and cy) and two minor jcv genotypes (b1-a1 and sc). this was contrasted with the jcv genotype profile in modern taiwanese: one major (sc) and two minor genotypes (cy and b1-a1 ... | 1999 | 10446645 |
| the high incidence of jc virus infection in urothelial carcinoma tissue in taiwan. | human polyomaviruses, jc virus (jcv) and bk virus (bkv), usually remain latent in kidney and urothelial tissue after primary infection. infection with human polyomavirus has still not been correlated conclusively with malignancy of kidney and urothelial tissue. the present study investigated further the possible relationship between jcv/bkv infection and urothelial carcinoma. tissue samples were examined from 33 urothelial carcinomas and 5 renal cell carcinomas for jcv/bkv infection, using neste ... | 2011 | 22012728 |
| prevalence and genotype identification of human jc virus in colon cancer in taiwan. | although jc virus (jcv), a human polyomavirus, has been detected in colon cancers, the association between jcv and colon cancer remains controversial. in taiwan, the prevalence of jcv infection in colon cancer patients has not been reported. thus, the purpose of this study was to investigate jcv infection in colon cancers in taiwan. formalin-fixed, paraffin-embedded tissues from 22 colon cancer patients were examined in this study. nested pcr was performed to detect viral genomic dna. the produc ... | 2008 | 18712832 |
| high incidence of jc viruria in jc-seropositive older individuals. | the prevalence of the human jc virus (jcv) in the general population at various ages was investigated. polymerase chain reaction was employed to detect viral dna in the urine. the results showed that the incidence of jc viruria was low in the young population, but it was high in the elderly. hemagglutination inhibition assay was performed for jcv seroprevalence study. the results showed that the seropositive rate of jcv was lower in children than that in adults. the ratio of viruria to seroposit ... | 2002 | 12402171 |
| incidence of jc viruria is higher than that of bk viruria in taiwan. | to investigate the prevalence of human polyomaviruses in taiwan, urine samples from immunocompetent (healthy), transient immunocompromised (pregnant), and prolonged immunosuppressed (autoimmune disease) individuals were collected throughout the island. the viral dna in the urine was detected by the polymerase chain reaction (pcr) and southern blot. the viral genotypes were determined by dna sequencing within the regulatory region. the overall results, including cases reported previously, show th ... | 1997 | 9210032 |
| different genotypes of human polyomaviruses found in patients with autoimmune diseases in taiwan. | we have assayed for the presence of human polyomaviruses in urine of autoimmune disease patients, such as systemic lupus erythematosus (sle), sjogren's syndrome (ss), rheumatoid arthritis (ra), or dermatomyositis/polymositis (dm/pm), by pcr. the results indicate that approximately 40% of patients were jcv positive and 15% of the jcv positive patients were also infected by bkv at the same time according to southern blot and dna sequencing of the pcr products. interestingly, the jcv present in aut ... | 1996 | 8835356 |