| molecular epidemiology of mycobacterium avium complex isolated from patients with and without aids in brazil and england. | mycobacterium avium complex (mac) is ubiquitous throughout the world. it is an opportunistic pathogen in aids patients but the number of cases in hiv negative patients is also increasing. the aim of this study was to determine whether patients were being infected with different mac strains or whether one strain was dominant. dna obtained from isolates in brazil and england were compared using pulsed field gel electrophoresis (pfge). strains from 22 brazilian patients clustered into 7 groups but ... | 1999 | 10459647 |
| increasing reports of non-tuberculous mycobacteria in england, wales and northern ireland, 1995-2006. | non-tuberculous mycobacteria have long been identified as capable of causing human disease and the number at risk, due to immune-suppression, is rising. several reports have suggested incidence to be increasing, yet routine surveillance-based evidence is lacking. we investigated recent trends in, and the epidemiology of, non-tuberculous mycobacterial infections in england, wales and northern ireland, 1995-2006. | 2010 | 20950421 |
| opportunist mycobacteria in england and wales: 1982 to 1994. | three thousand and fifty-two infections with opportunist mycobacteria were reported to the phls communicable disease surveillance centre from 1982 to 1994. the commonest reported species was mycobacterium avium-intracellulare (mai), followed by m. kansasii and m. malmoense. the annual totals of opportunist mycobacteria increased steadily over this period, mostly, but not exclusively, due to an increase in reports of mai associated with hiv infection. there were also increases in reports of mai n ... | 1996 | 8917989 |
| an outbreak of multi-drug-resistant tuberculosis in a london teaching hospital. | we describe the epidemiology and control of a hospital outbreak of multi-drug-resistant tuberculosis (mdr-tb). a human immunodeficiency virus (hiv)-negative patient with drug-sensitive tuberculosis developed mdr-tb during a period of unsupervised therapy. she was admitted to an isolation room in a ward with hiv-positive patients, but the room, unbeknown to hospital staff, was at positive-pressure relative to the main ward. seven hiv-positive contacts developed mdr-tb. the diagnosis in the second ... | 1998 | 9651855 |
| pulmonary mycobacterium avium-intracellulare is the main driver of the rise in non-tuberculous mycobacteria incidence in england, wales and northern ireland, 2007-2012. | the incidence of non-tuberculous mycobacteria (ntm) isolation from humans is increasing worldwide. in england, wales and northern ireland (ew&ni) the reported rate of ntm more than doubled between 1996 and 2006. although ntm infection has traditionally been associated with immunosuppressed individuals or those with severe underlying lung damage, pulmonary ntm infection and disease may occur in people with no overt immune deficiency. here we report the incidence of ntm isolation in ew&ni between ... | 2016 | 27154015 |
| non-tuberculous slow-growing mycobacterial pulmonary infections in non-hiv-infected patients in south london. | uk data on slow-growing non-tuberculous mycobacterial (ntm) pulmonary infections are sparse and there is little consensus on optimal treatment regimens. | 2012 | 23078529 |