| fluctuations in climate and incidence of coccidioidomycosis in kern county, california: a review. | coccidioidomycosis (valley fever) is a fungal infection found in the southwestern united states, northern mexico, and some places in central and south america. the fungi that cause it (coccidioides immitis and coccidioides posadasii) are normally soil dwelling, but, if disturbed, become airborne and infect the host when their spores are inhaled. it is thus natural to surmise that weather conditions, which foster the growth and dispersal of coccidioides, must have an effect on the number of cases ... | 2007 | 17347336 |
| antifungal susceptibility profiles of coccidioides immitis and coccidioides posadasii from endemic and non-endemic areas. | coccidioidomycosis is a systemic fungal infection endemic in southwestern united states, mexico, central and south america. the causal agents are coccidioides immitis and c. posadasii. a large number of cases of coccidioidomycosis in new york state residents were identified. we compared susceptibility profiles of these isolates and of c. immitis isolates from california using mycelial phase inoculum and clsi (nccls) m38-a broth microdilution protocol. minimum fungicidal concentrations (mfc) were ... | 2007 | 17484074 |
| increase in coccidioidomycosis - california, 2000-2007. | coccidioidomycosis is an infection resulting from inhalation of airborne spores of coccidioides immitis or coccidioides posadasii, soil-dwelling fungi endemic to california's san joaquin valley; southern regions of arizona, utah, nevada, and new mexico; western texas; and regions of mexico and central and south america. of an estimated 150,000 new infections annually in the united states, approximately 60% are asymptomatic. patients with symptoms usually experience a self-limited influenza-like ... | 2009 | 19214158 |
| population genomic sequencing of coccidioides fungi reveals recent hybridization and transposon control. | we have sequenced the genomes of 18 isolates of the closely related human pathogenic fungi coccidioides immitis and coccidioides posadasii to more clearly elucidate population genomic structure, bringing the total number of sequenced genomes for each species to 10. our data confirm earlier microsatellite-based findings that these species are genetically differentiated, but our population genomics approach reveals that hybridization and genetic introgression have recently occurred between the two ... | 2010 | 20516208 |
| use of population genetics to assess the ecology, evolution, and population structure of coccidioides. | during the past 20 years, a general picture of the genetic diversity and population structure of coccidioides, the causal agent of coccidioidomycosis (valley fever), has emerged. the genus consists of 2 genetically diverse species, c. immitis and c. posadasii, each of which contains 1 or more distinct populations with limited gene flow. genotypic data indicate that c. immitis is divided into 2 subpopulations (central and southern california populations) and c. posadasii is divided into 3 subpopu ... | 2016 | 27191589 |
| local population structure and patterns of western hemisphere dispersal for coccidioides spp., the fungal cause of valley fever. | coccidioidomycosis (or valley fever) is a fungal disease with high morbidity and mortality that affects tens of thousands of people each year. this infection is caused by two sibling species, coccidioides immitis and c. posadasii, which are endemic to specific arid locales throughout the western hemisphere, particularly the desert southwest of the united states. recent epidemiological and population genetic data suggest that the geographic range of coccidioidomycosis is expanding, as new endemic ... | 2016 | 27118594 |