| indolizidine, antiinfective and antiparasitic compounds from prosopis glandulosa var. glandulosa. | a new potent antiinfective and antiparasitic 2,3-dihydro-1h-indolizinium chloride (1) was isolated from prosopis glandulosa var. glandulosa. three additional new (2-4) and one known (5) indolizidines were also isolated, and the dihydrochloride salts of 1-3 (compounds 6, 7, and 8) were prepared. structures were determined by 1d and 2d nmr and mass spectra. compound 1 showed potent in vitro antifungal activity against cryptococcus neoformans and aspergillus fumigatus (ic(50) values = 0.4 and 3.0 m ... | 2009 | 19105653 |
| antiparasitic and antimicrobial indolizidines from the leaves of prosopis glandulosa var. glandulosa* | a new indolizidine alkaloid, named +ö(1,6)-juliprosopine ( 1), together with previously known indolizidine analogs ( 2- 6), was isolated from the leaves of prosopis glandulosa var. glandulosa, collected from nevada, usa; while two other known indolizidines, juliprosopine ( 6) and juliprosine ( 7), were isolated from p. glandulosa leaves collected in texas, usa. the structures of compound 1 and 7 were determined using a combination of nmr and ms techniques. compound 7 exhibited potent antiplasmod ... | 2011 | 21384317 |