| clinical profile of adult cystic fibrosis patients with frequent epidemic clones of pseudomonas aeruginosa. | earlier reports suggested that pseudomonas aeruginosa frequent epidemic clones circulating in cystic fibrosis (cf) centres had increased virulence. however, recent data show no consistent associations with virulence, and suggest attenuation of virulence in chronic infection. changes to infection control programmes in relation to frequent epidemic clones should be based on their frequency, virulence across all age groups and mode of acquisition. the australian epidemic strain-1 (aes-1) (or the me ... | 2010 | 20573059 |