Publications

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the association of mycoplasma hominis, ureaplasma urealyticum and mycoplasma genitalium with bacterial vaginosis: observations on heterosexual women and their male partners.the prevalence of 3 mycoplasmas (mycoplasma hominis, ureaplasma urealyticum and mycoplasma genitalium) was determined in a cohort of women with or without bacterial vaginosis (bv) and in their respective male partners. heterosexual women with or without bv and their male partners were recruited and genital sampling for these microorganisms was performed. seventeen women with bv and 21 women with normal flora, and their respective male partners, were recruited. m. hominis was present in 9 (53%) o ...200010872907
prevalence of mycoplasma genitalium in early pregnancy and relationship between its presence and pregnancy outcome.mycoplasma genitalium is associated with cervicitis and pelvic inflammatory disease but little is known about its role in pregnancy. we investigated the prevalence of m. genitalium by polymerase chain reaction assay on urine specimens from 1216 pregnant women (mean age 31years) presenting before 10 weeks of gestation in 32 general practices. the prevalence of m. genitalium was 0.7% (6/915, 95% ci 0.1-1.2). it was more common in women aged < 20 years, women of afro-caribbean or black african ethn ...200415663138
prevalence, clinical features and quantification of genital non-viral infections.we conducted a study of the prevalence, clinical features and microscopy findings, by retrospective case-notes survey, of six non-viral organisms, among 1718 attendees at a genitourinary (gu) medicine clinic in england. an in-house assay for six non-viral infections was used and quantitation of ureaplasmas performed. the prevalences of the six organisms were: chlamydia trachomatis (ct), 7.1%; neisseria gonorrhoeae (ng), 0.6%; mycoplasma genitalium (mg), 1.0%; trichomonas vaginalis, 0.2%; ureapla ...201323970658
mycoplasma genitalium in chronic non-gonococcal urethritis.seventy-eight men with a history of chronic urethritis were referred for investigation. of 52 men diagnosed as having persistent or recurrent non-gonococcal urethritis (ngu) at the time of referral, 11 (21%) were infected with mycoplasma genitalium and three with chlamydia trachomatis. men who were m. genitalium-positive had not previously received less antibiotic, in terms of treatment duration, than those who were m. genitalium-negative, suggesting a possible resistance to the antibiotics give ...200414769166
detection of mycoplasma genitalium in the genitourinary tract of women by the polymerase chain reaction.a polymerase chain reaction (pcr) was used to demonstrate the presence or absence of mycoplasma genitalium in the lower genital tract of 57 women who attended a sexually transmitted diseases clinic. the mycoplasma was detected in the cervix of 10 (17.5%) women and also in the vagina of 4 (16%) and the urethra of 6 (24%) of 25 women from whom multiple samples were obtained. chlamydia trachomatis was detected also by a pcr in 9 (16%) of the women, but only 3 were chlamydia-positive and mycoplasma- ...19911911958
a cross-sectional study of mycoplasma genitalium infection and correlates in women undergoing population-based screening or clinic-based testing for chlamydia infection in london.to determine mycoplasma genitalium infection and correlates among young women undergoing population-based screening or clinic-based testing for chlamydia infection.201424503298
the prevalence of urethral and rectal mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic.to determine the prevalence of rectal and urethral mycoplasma genitalium (mg) in men who have sex with men (msm) attending a genitourinary medicine clinic and to measure its associations with symptoms, clinical signs, sexual behaviour and concomitant sexually transmitted infections (sti).201019843536
mycoplasma genitalium is associated with symptomatic urethritis.in order to further investigate the epidemiology of mycoplasma genitalium, 680 men attending departments of genitourinary medicine in bristol, bath and truro were studied. m. genitalium was detected in 36 men (5.3%) and was present at all three clinics. clinically, both urethritis and the presence of a urethral discharge and/or dysuria, but not penile irritation were independently associated with the detection of m. genitalium, the former being with the strongest association (odds ratio [or] 10. ...200616643675
detection of markers predictive of macrolide and fluoroquinolone resistance in mycoplasma genitalium from patients attending sexual health services in england.resistance to both macrolides and fluoroquinolones has been reported in mycoplasma genitalium; however, due to limited diagnostics, studies are often small and confined to specific geographical areas. this study sought to determine the rate of predicted resistance in m. genitalium-positive specimens referred for diagnostic testing.201728717051
apparently-different clearance rates from cohort studies of mycoplasma genitalium are consistent after accounting for incidence of infection, recurrent infection, and study design.mycoplasma genitalium is a potentially major cause of urethritis, cervicitis, pelvic inflammatory disease, infertility, and increased hiv risk. a better understanding of its natural history is crucial to informing control policy. two extensive cohort studies (students in london, uk; ugandan sex workers) suggest very different clearance rates; we aimed to understand the reasons and obtain improved estimates by making maximal use of the data from the studies. as m. genitalium is a sexually-transmi ...201626910762
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