| hiv-1-associated kaposi's sarcoma in a predominantly black population at an inner city hospital. | kaposi's sarcoma (ks) associated with human immunodeficiency virus type 1 (hiv-1) is the most common malignancy in patients with aids. it has been most commonly reported in white homosexual men, though a few cases have been reported in blacks. | 1998 | 9634116 |
| evidence for concurrent epidemics of human herpesvirus 8 and human immunodeficiency virus type 1 in us homosexual men: rates, risk factors, and relationship to kaposi's sarcoma. | we examined human herpesvirus 8 (hhv-8) seroprevalence and seroincidence among 245 homosexual men from new york city (nyc) and washington, dc (dc) who have been followed since 1982. an immunofluorescence assay measured antibodies to a latent hhv-8 nuclear antigen. seroprevalence was 20.4% in 1982; seroincidence was approximately 15%/year during 1982-1983 but fell sharply thereafter. nyc men had a higher seroprevalence (odds ratio, 3.43; p<.001) and seroincidence (rate ratio, 2.13; p=.01) than dc ... | 1999 | 10479125 |
| human herpesvirus 8 infection and kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women. | little is known about the epidemiology of human herpesvirus 8 (hhv-8) infections among women. a cross-sectional study was conducted of hhv-8 infection among human immunodeficiency virus (hiv)-infected and high-risk hiv-uninfected women. serological tests with noninduced (latent) and induced (lytic) hhv-8 antigens were used to detect infection among 2483 participants of a multisite cohort. reactivity to latent antigen was present in 4.1% and to induced antigens in 12.0% of women. seven of 8 women ... | 2001 | 11237842 |
| kaposi's sarcoma in three hiv-1-infected cohorts. | we describe the kaposi's sarcoma (ks) experience in three cohorts of homosexual men, subjects with hemophilia, and human immunodeficiency virus type 1 (hiv-1) seroconverters. the risk of ks was higher in hiv-1-infected homosexual men from new york city as compared with washington, d.c. and was very low in the hemophilia subjects. while ks accounted for a decreasing proportion of aids cases in homosexual men, the absolute risk per year did not diminish. survival was similar after diagnosis of ks ... | 1990 | 2395084 |
| immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. | since prevalent cohorts may be biased by the duration of human immunodeficiency virus (hiv) infection (onset bias), it is useful to assess the potential predictive value of markers in incident cohorts of hiv-positive subjects for whom the date of seroconversion is known or can reliably be estimated. of 131 homosexual men with hiv-1 seroconversion from new york city and washington, dc, who were evaluated annually beginning in 1982, 60 developed acquired immunodeficiency syndrome (aids) by the end ... | 1992 | 1384311 |
| human herpesvirus 8 seroprevalence among prostate cancer case patients and control subjects. | to investigate a possible association between human herpesvirus 8 (hhv-8) and prostate cancer, we evaluated hhv-8 seroprevalence in 2 case-control studies. hhv-8 antibodies were detected by immunofluorescence with cells expressing lytic viral proteins and by enzyme immunoassays with recombinant viral structural protein (k8.1) and latent protein (latency-associated nuclear antigen-1; open reading frame 73), respectively. hhv-8 seroprevalence tended to be lower in patients with prostate cancer tha ... | 2007 | 17570107 |
| effect of t4 count and cofactors on the incidence of aids in homosexual men infected with human immunodeficiency virus. | we prospectively evaluated potential markers and cofactors for the acquired immunodeficiency syndrome (aids) in 86 homosexual men who were seropositive for human immunodeficiency virus antibodies. during three years of follow-up, 19 men developed aids. risk of aids was clearly predicted by the total number of circulating okt4-positive lymphocytes (t4 count) at enrollment, while the corresponding t8 count was unrelated to subsequent aids development. subjects in manhattan had a higher risk of kap ... | 1987 | 3491911 |