Publications

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[epidemiological analysis of poliomyelitis cases in 1994, china].in 1994, the number of reported polio cases was 307 in china. this number was 53% lower than that in 1993, and was the lowest record ever in china. in 1994, the distribution of polio cases was highly dispersed and the number of outbreak was reduced obviously. of 225 counties which reported polio cases in 1994, polio outbreak occured in 2 counties. cases due to polio outbreak accounted for 4.2% of the total cases. the distribution of polio wild virus was narrow but the regional difference still e ...19958728953
[an epidemiological study on vaccine derived polio virus circle in zhenfeng county of guizhou province].to analyze the event and cause of vaccine derived polio virus (vdpv) circle happened at yaoshang village, wanlan township, zhenfeng county, qianxinan prefecture, guizhou province in august 2004.200516266542
[study on an epidemic caused by the vaccine-derived poliovirus circulation in guizhou province, 2004].to study the circulating vaccine-derived poliovirus (cvdpvs) that occurred in zhenfeng county, guizhou province in 2004 and to discover wild-poliovirus, vaccine-derived poliovirus (vdpvs) and other vaccine-associated poliovirus which could cause clinical poliomyelitis.200516390000
[reevaluate the effect of g-480 point mutation that determines the neurovirulence of type i vaccine polioviruses].whole genome sequencing of 9 type i circulating vaccine-derived polioviruses (cvdpvs) isolated in guizhou province in china revealed that reverse mutations did not occur in g-480 and u-525 which are known as the most important neurovirulence determinate sites, while other known neurovirulence determinate sites such as a-2438, a-2795, c-6203 and g-7441 did revert to mahoney type. 5 type i cvdpvs were selected for neurovirulence test on pvr-tg21 transgenic mice which express human poliovirus recep ...200717886713
an outbreak of poliomyelitis caused by type 1 vaccine-derived poliovirus in china.in may-july 2004, type 1 vaccine-derived poliovirus (vdpv) was isolated from 2 case patients with polio and a contact of a third case patient in guizhou province.200616897650
an insight into recombination with enterovirus species c and nucleotide g-480 reversion from the viewpoint of neurovirulence of vaccine-derived polioviruses.a poliomyelitis outbreak caused by type 1 circulating vaccine-derived polioviruses (cvdpvs) was identified in china in 2004. six independent cvdpvs (eight isolates) could be grouped into a single cluster with pathways of divergence different from a single cvdpv progenitor, which circulated and evolved into both a highly neurovirulent lineage and a less neurovirulent lineage. they were as neurovirulent as the wild type 1 mahoney strain, recombination was absent, and their nucleotide 480-g was ide ...201526603565
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