Publications

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guillain barre syndrome: the leading cause of acute flaccid paralysis in hazara division.acute flaccid paralysis (afp) can be caused by a number of conditions. a common preventable cause is poliomyelitis which is still being reported in pakistan, guillain barre syndrome (gbs), also known as acute inflammatory demyelinating polyneuropathy, is another common cause of acute flaccid paralysis. it is important to recognize gbs in childhood as parents consider all acute flaccid paralysis to be due to poliomyelitis. the present study was designed to know the frequency of different causes o ...200717867475
identification of new genotype of echovirus 19 from children with acute flaccid paralysis in pakistan.enteroviruses are known to cause childhood paralysis. the purpose of this study was to examine the genetic diversity and to determine the association of non-polio enteroviruses (npevs) with acute flaccid paralysis (afp). stool samples (n = 1191) of children with afp were collected from khyber pakhtunkhwa and federally administered tribal areas of pakistan. poliovirus was isolated in 205 (17.2%) samples and npevs were found in 215 (18.0%) samples. out of 215 viruses, 124 (57.7%) were typed into 1 ...201526644348
progress toward poliomyelitis eradication - pakistan, january 2015-september 2016.pakistan, afghanistan, and nigeria remain the only countries where endemic wild poliovirus type 1 (wpv1) transmission continues. this report describes the activities, challenges, and progress toward polio eradication in pakistan during january 2015-september 2016 and updates previous reports (1,2). in 2015, a total of 54 wpv1 cases were reported in pakistan, an 82% decrease from 2014. in 2016, 15 wpv1 cases had been reported as of november 1, representing a 61% decrease compared with the 38 case ...201627880752
progress toward poliomyelitis eradication--pakistan, january 2014-september 2015.since nigeria reported its last case of wild poliovirus type 1 (wpv1) in july 2014, pakistan and afghanistan remain the only two countries where wpv transmission has never been interrupted. this report describes actions taken and progress achieved toward polio eradication in pakistan during january 2014-september 2015 and updates previous reports. a total of 38 wpv1 cases were reported in pakistan during january-september 2015, compared with 243 during the same period in 2014 (an 84% decline). a ...201526584026
a new method for estimating the coverage of mass vaccination campaigns against poliomyelitis from surveillance data.mass vaccination campaigns with the oral poliovirus vaccine targeting children aged <5 years are a critical component of the global poliomyelitis eradication effort. monitoring the coverage of these campaigns is essential to allow corrective action, but current approaches are limited by their cross-sectional nature, nonrandom sampling, reporting biases, and accessibility issues. we describe a new bayesian framework using data augmentation and markov chain monte carlo methods to estimate variatio ...201526568569
progress and peril: poliomyelitis eradication efforts in pakistan, 1994-2013.pakistan is one of 3 countries where transmission of indigenous wild poliovirus (wpv) has never been interrupted. numbers of confirmed polio cases have declined by >90% from preeradication levels, although outbreaks occurred during 2008-2013. during 2012 and 2013, 58 and 93 wpv cases, respectively, were reported, almost all of which were due to wpv type 1. of the 151 wpv cases reported during 2012-2013, 123 (81%) occurred in the conflict-affected federally administered tribal areas (fata) and in ...201425316830
progress toward poliomyelitis eradication - pakistan, january 2012-september 2013.pakistan is one of three countries where transmission of indigenous wild poliovirus (wpv) has never been interrupted. this report describes polio eradication activities and progress in pakistan during january 2012-september 2013 and updates previous reports. during 2012, 58 wpv cases were reported in selected areas, compared with 198 cases throughout the country in 2011; 52 wpv cases were reported during january-september 2013, compared with 54 cases during the same period in 2012. of the 110 wp ...201324257203
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