Publications

molecular epidemiology of an outbreak of poliomyelitis in south africa in 1987/1988.	an outbreak of paralytic poliomyelitis occurred in the republic of south africa in 1987/88. the epidemic took place in the natal/kwazulu region of south africa and was due to type 1 poliovirus. twenty-four isolates were characterised by 1- and 2-dimensional oligonucleotide mapping and a single strain of wild-type poliovirus was identified. the same strain of virus was also isolated in other areas of south africa at the time of the outbreak and has persisted into 1989.	1991	1662703
poliomyelitis outbreak in natal/kwazulu, south africa, 1987-1988. 2. immunity aspects.	an extensive poliomyelitis outbreak due to type 1 poliovirus took place in natal/kwazulu, south africa, in 1987-1988, causing 412 paralytic cases. this epidemic differed from a previously described outbreak in gazankulu, south africa, in 1982 in that it occurred against a background of relatively good immunity. thus, only 12% of patients lacked antibodies to types 2 and 3, indicating lack of previous immunization, and 76% of healthy children sampled in the epidemic area had serological immunity ...	2004	1566318
molecular characterisation of type 1 polioviruses associated with epidemics in south africa.	the molecular epidemiology of wild-type 1 polioviruses isolated in south africa during 2 major poliomyelitis epidemics in the 1980s and during the pre- and inter-epidemic periods was investigated by partial sequence analysis across the vp1/2a junction. poliovirus-specific primers were used to amplify and subsequently sequence the region of interest. viruses belonging to different genotypes were found to have been responsible for the 2 outbreaks. the gazankulu outbreak in 1982 was caused by a pol ...	1997	9131457