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north american blastomycosis: a review.north american blastomycosis, first reported in 1894, and once thought to be a geographically localized disease, has now been reported worldwide. the greatest number of cases occur in the mississippi, missouri, and ohio river basins. the organism enters the body via the lungs with subsequent dissemination to other organs, including the skin, eyes, bones, and genitourinary system. patients most often present with cutaneous or pulmonary complaints. demonstration of characteristic fungal morphology ...1979391499
epidemiologic aspects of blastomycosis, the enigmatic systemic mycosis.a growing body of epidemiologic information derives from the study of sporadic cases and seven epidemics of blastomycosis, although a complete epidemiologic description of the disease is impeded by the absence of a skin test and difficulty isolating the causative fungus, blastomyces dermatitidis, from nature. most cases occur sporadically in humans and dogs in a worldwide distribution. endemic areas in the united states include southeastern, southcentral, and midwestern states, particularly arka ...19863317597
expanding epidemiology of blastomycosis: clinical features and investigation of 2 cases in colorado.on the basis of case reports of blastomycosis, blastomyces dermatitidis is widely accepted to be endemic in the central united states in and around the ohio and mississippi river valleys. blastomycosis also occurs in parts of canada and in the southeastern united states. however, there has been no large-scale skin testing, and the environmental range of b. dermatitidis may have been underestimated. we describe 2 immunocompetent patients with blastomycosis acquired while working in the front rang ...200010722448
blastomycosis: organ involvement and etiologic diagnosis. a review of 123 patients from mississippi.blastomycosis can only be diagnosed through the identification of the yeasts of blastomyces dermatitidis in body fluids, tissues, or cultured material. the charts from 123 patients treated for blastomycosis at the university of mississippi medical center from january 1980 through may 2000 were reviewed to determine the role of wet preparation, cytology, histology, and culture in diagnosing this fungal disease. cytology uncovered the etiologic agent in 56.1% of all cases and in 71.8% of pulmonary ...200011149972
serological differences in two blastomyces dermatitidis isolates from different geographical regions of north america.yeast phase lysate antigens were prepared from two isolates (t-58 and erc-2) from different geographic locations. tennessee and wisconsin. these lysate were evaluated with respect to their ability to detect antibody in dogs infected with blastomycosis and rabbits immunized with the lysates by an enzyme linked immunosorbent assay (elisa). both the dog sera and rabbit sera assays demonstrated that there were serological differences in these two isolates, which implied that there was antigenic vari ...200211998876
phylogeographic analysis of blastomyces dermatitidis and blastomyces gilchristii reveals an association with north american freshwater drainage basins.blastomyces dermatitidis and blastomyces gilchristii are dimorphic fungal pathogens that cause serious pulmonary and systemic infections in humans. although their natural habitat is in the environment, little is known about their specific ecologic niche(s). here, we analyzed 25 microsatellite loci from 169 strains collected from various regions throughout their known endemic range in north america, representing the largest and most geographically diverse collection of isolates studied to date. g ...201627428521
a laboratory-based surveillance of human blastomycosis in wisconsin between 1973 and 1982.blastomycosis appears to be prevalent in states around the great lakes. however, its incidence in these states has not been reported. the wisconsin division of health established a laboratory-based surveillance for human blastomycosis in wisconsin to estimate disease incidence and identify endemic areas in the state for the interval 1973 to 1982. certified mycology and pathology laboratories in wisconsin and at two major medical centers in minnesota were surveyed for all laboratory isolates and ...19854050777
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