a nosocomial outbreak of parvovirus b19 infection. | | 1992 | 1284951 |
parvovirus b19 outbreak in a children's ward. | parvovirus b19 infection can cause severe complications in pregnant women, individuals with haemolytic anaemia, and those who are immunocompromised. in a hospital outbreak of this infection, a balance should be struck between protection of these individuals and the maintenance of medical services. the index case of an outbreak of parvovirus b19 infection among staff and patients of a paediatric ward was not identified. 58 members of staff were screened for b19 markers and 4 of the 6 susceptible ... | 1992 | 1345828 |
clinical manifestations of human parvovirus b19 in adults. | human parvovirus b19 has been associated with various clinical effects in a number of uncontrolled reports. to define the usual manifestations of b19 infection in adults and the factors that influence them we present a clinicoepidemiological study of an outbreak of b19 infection centered on a junior school. four hundred fifty-three of 475 adults in this community were interviewed and blood was obtained for serological diagnosis. fifty-four cases of recent infection were identified and were hla t ... | 1989 | 2541666 |
erythema infectiosum in a primary school: investigation of an outbreak in bury. | between january and april 1987, 97 of 302 (32%) children attending a primary school in bury, lancashire, were affected by an exanthematous illness. the duration and extent of the episode caused considerable local interest and anxiety. examination of 6 serum specimens obtained during the subsequent investigation demonstrated evidence of recent human parvovirus b19 infection in 3 children and 1 teacher. no evidence of recent rubella virus infection was found. the investigation of the episode is di ... | 1989 | 2552489 |
pruritus in parvovirus infection. | an outbreak of slapped cheek syndrome (erythema infectiosum) occurred in chepstow between march and june 1986. about 50 children with the illness were seen in one general practice. during the same period five women in the practice developed arthritis associated with human parvovirus infection and four of them suffered marked pruritus. it is suggested that if pruritus is a feature in any patient with an acute onset arthritis, parvovirus infection should be considered as a possible cause. | 1987 | 2826779 |
dual infection with rubella and human parvovirus. | | 1985 | 2863648 |
human parvovirus and rubella-like illness. | | 1985 | 2863649 |
sex ratio in outbreaks of parvovirus b19 infection. | | 1987 | 2885591 |
parvovirus infection in hospital practice. | eleven cases of human parvovirus (hpv) infection were diagnosed on the basis of positive igm serology over a 9-month period in two london hospitals. these cases accounted for almost 30% of viral illness in which hpv serology had been requested. ten of the cases presented with joint symptoms and/or rash and one case presented with evidence of a severe autoimmune haemolytic anaemia. six patients had lymphadenopathy. clinical and laboratory features of the cases are presented. hpv dna was sought bu ... | 1987 | 3028563 |
preliminary development of a live attenuated canine parvovirus vaccine from an isolate of british origin. | canine parvovirus isolated from a case of haemorrhagic enteritis in a breeding kennel in england was passaged and cloned in cultured feline and canine cells. no significant evidence of pathogenicity was found during six serial passages of the modified virus back through young dogs. the attenuated virus was excreted by inoculated animals and spread rapidly to uninoculated animals held in contact. when high titre attenuated virus was given to the six-week-old offspring of a seropositive dam a prom ... | 1987 | 3035779 |
acute admissions of patients with sickle cell disease who live in britain. | all acute admissions of patients with sickle cell disease who lived in the london borough of brent and attended this hospital were analysed for a period of one year. sixty three of the 211 patients who were followed up by the haematology department required 161 acute admissions during the year. most admissions (126) were for the 42 patients with homozygous sickle cell disease; 147 (91%) were for vaso-occlusive episodes, 142 of which were for painful crises, three for cerebrovascular accidents, a ... | 1987 | 3109583 |
increased incidence of anti-glomerular basement membrane antibody (anti-gbm) nephritis in the mersey region, september 1984-october 1985. | we report an increase in the incidence of anti-glomerular basement membrane antibody nephritis in the mersey region over the 13 months from september 1984 to october 1985. during this period anti-glomerular basement membrane antibody nephritis was diagnosed in 10 patients: seven cases occurred between 1 june and 31 october 1985. we could identify no common infective agent or history of toxic exposure. although outbreaks of parvovirus infection were reported in the region during this period, no p ... | 1988 | 3256901 |
the prevalence of antibody to human parvovirus b19 in england and wales. | the prevalence of antibody to human parvovirus b19 (anti-b19 igg) in england and wales was measured by an antibody-capture radioimmunoassay. over 2000 sera were examined; 1422 from the general population, 374 from unselected children admitted to hospital and 300 from women attending an antenatal clinic. waning levels of maternally-derived antibody were found in infants under 1 year old. in children 1-5 years old, 5-15% had anti-b19 igg and this rose to 50-60% in older children, young adults and ... | 1988 | 3339634 |
parvovirus vaccination. | | 1985 | 4024444 |
an outbreak of erythema infectiosum associated with human parvovirus infection. | erythema infectiosum (ei) or fifth disease is a mild, acute exanthematous disease, occurring mainly among children, for which a causative virus has long been sought. in may 1983 an outbreak of exanthematous illness was reported in a primary school in north london. children attending the school were investigated by questionnaire and 162 (43.9%) reported an illness with the features of ei. in each of 36 cases investigated virologically the illness was associated with parvovirus infection. moreover ... | 1984 | 6086750 |
human parvovirus, the cause of erythema infectiosum (fifth disease)? | | 1983 | 6134148 |
canine parvovirus infection. | | 1980 | 7210433 |
canine parvovirus infection. | | 1980 | 7445338 |
observational study of effect of intrauterine transfusions on outcome of fetal hydrops after parvovirus b19 infection. | the role of intrauterine transfusion for fetal hydrops arising from maternal paravirus b19 infection is unclear. 66 cases of fetal hydrops arising from b19 infection were reported in england and wales between june, 1992, and september, 1994. in 29 cases the fetus was dead at the time of the first abnormal ultrasound or a therapeutic abortion as performed; 12 of the 38 alive at the first abnormal scan received intrauterine transfusions and 3 of the 12 died. 26 did not receive intrauterine transfu ... | 1995 | 7475774 |
parvovirus b19 outbreak on an adult ward. | in november and december 1992, an outbreak of parvovirus b19 infection occurred among patients and staff on an adult mixed surgical ward at a large hospital in london. three patients and 15 staff members were serologically confirmed as acute cases. the attack rate among susceptible members of staff was 47%. in those infected, arthralgia (80%) and rash (67%) were the most common symptoms. of six susceptible in-patients on the ward, three became infected. one of the in-patients who had carcinoma o ... | 1994 | 7925671 |
salivary diagnosis of measles: a study of notified cases in the united kingdom, 1991-3. | to validate a method for salivary diagnosis of measles and to assess the diagnostic accuracy of notified cases of measles. | 1994 | 8167513 |
a regional experience of red cell aplasia. | the incidence and current management of red cell aplasia in children was determined from a retrospective survey of haematologists and paediatricians in the northern health region of england over a 7-year period. thirty-three children were diagnosed: 4 had diamond blackfan anaemia, 22 transient erythroblastopenia of childhood, and 7 parvovirus b19 aplasia, with annual incidences of 1, 5 and 2 per 1,000,000 children respectively. many were over-investigated. three with diamond blackfan anaemia wer ... | 1993 | 8482277 |
effect of hla type and hypocomplementaemia on the expression of parvovirus arthritis: one year follow up of an outbreak. | to determine the effect of hla type and hypocomplementaemia on the duration and severity of joint involvement in parvovirus infection (hpv). | 1996 | 8572737 |
a school outbreak of parvovirus b19 infection investigated using salivary antibody assays. | an outbreak of parvovirus b19 infection at a primary school was investigated using saliva samples. antibody capture immunoassays for salivary b19 igg and igm were developed using a recombinant b19 antigen and monoclonal antibody to b19 virus. evaluation of the salivary igg assay using paired serum and saliva samples from 43 staff at st thomas' hospital showed that it had a sensitivity of 100% and a specificity of 95%. evaluation of the salivary b19 igm assay using 87 paired blood and saliva samp ... | 1996 | 8666078 |
increased incidence of parvovirus b19. | | 1997 | 9219425 |
zoonotic and viral infection in fetal loss after 12 weeks. | one hundred and thirty-six women from an urban, rural and farming community were recruited to a study of infectious causes of midtrimester miscarriage (n = 85), stillbirth (n = 32), or termination for developmental (n = 17) or chromosomal (n = 2) abnormalities. no woman had evidence of acute infection with toxoplasma, listeria, leptospira or chlamydia psittaci (ovine enzootic abortion). one woman had midtrimester miscarriage associated with primary cytomegolovirus infection and five women had ev ... | 1997 | 9255087 |
immediate and long term outcome of human parvovirus b19 infection in pregnancy. | to estimate more precisely the risk of fetal loss and congenital abnormalities after maternal parvovirus b19 infection, and to assess the long term outcome for surviving infants. | 1998 | 9501782 |
a comparison of oral fluid collection devices for use in the surveillance of virus diseases in children. | three oral fluid collection devices (orasure, omni-sal and oracol) were compared in terms of the quality of oral fluid collected by each device for antibody testing and their acceptability to participants. participants (143 children aged 3.5-5 y from north hertfordshire, uk, who had recently received dtap and mmr vaccination) were randomised to use one of the three types of collection device. oral fluid was collected by a parent who completed a short questionaire recording information on ease of ... | 2001 | 11429716 |
goose parvovirus in england and wales. | | 2004 | 15328745 |
eye anomalies: seasonal variation and maternal viral infections. | eye anomalies, including anophthalmos and microphthalmos (absent eye and small eye), are common features in congenital infection syndromes such as rubella. influenza, coxsackie virus, and parvovirus are less well-established teratogens. we report an ecologic analysis of anophthalmia/microphthalmia prevalence in england in relation to temporal variation in these infections using routine infection data. | 2005 | 15824546 |
the burden of parvovirus b19 infection in women of childbearing age in england and wales. | a serological survey has been used to investigate the epidemiology of parvovirus b19 infection in england and wales. a total of 2835 sera representing the complete age range were selected from a convenience collection obtained in 1996 that reflects the general population and screened for parvovirus b19-specific igg. antibody prevalence rose nonlinearly with age from 21% in those aged 1-4 years to >75% in adults aged > or = 45 years. force-of-infection estimates were similar to those previously m ... | 2007 | 17291377 |
comparison of tissue distribution, persistence, and molecular epidemiology of parvovirus b19 and novel human parvoviruses parv4 and human bocavirus. | parv4 and human bocavirus (hbov) are newly discovered human parvoviruses with poorly understood epidemiologies and disease associations. we investigated the frequencies of persistence, tissue distribution, and influence of immunosuppression on replication of these viruses. | 2007 | 17397006 |
serological survey of virus infection among wild house mice (mus domesticus) in the uk. | the serological prevalence of 13 murine viruses was surveyed among 103 wild-caught and 51 captive-bred house mice (mus domesticus), originating from several trapping locations in northwest england, using blood samples obtained during routine health screening of an established wild mouse colony. a high proportion of recently caught wild mice were seropositive for mouse hepatitis virus (86%), mouse cytomegalovirus (79%), mouse thymic virus (78%), mouse adenovirus (68%), mouse parvovirus (59%) and ... | 2007 | 17430622 |
spatiotemporal patterns and risks of herd breakdowns in pigs with postweaning multisystemic wasting syndrome. | a retrospective cohort study of 116 british pig farms was undertaken to investigate the epidemiological risk factors associated with herd breakdowns with postweaning multisystemic wasting syndrome (pmws). farmers reported the pmws status of their herd (case definition 1) and, where applicable, when the disease was first suspected and what they observed; they described a prolonged increase in mortality in six to 16-week-old pigs that was not attributable to any disease known to be on their farm. ... | 2007 | 17545645 |
parvovirus b19 infection in five european countries: seroepidemiology, force of infection and maternal risk of infection. | we conducted a seroprevalence survey in belgium, finland, england & wales, italy and poland on 13 449 serum samples broadly representative in terms of geography and age. samples were tested for the presence of immunoglobulin g antibody using an enzyme immunoassay. the age-specific risk of infection was estimated using parametric and non-parametric statistical modelling. the age-specific risk in all five countries was highest in children aged 7-9 years and lower in adults. the average proportion ... | 2008 | 17956642 |
isolation in cell cultures and initial characterisation of two novel bocavirus species from swine in northern ireland. | we report the isolation in cell cultures of two novel bocavirus species in pigs from farms in northern ireland with clinical postweaning multisystemic wasting syndrome (pmws). we have designated the isolates as porcine bocavirus-3 (pbov3) and porcine bocavirus-4 (pbov4). to date 5082 and 4125bps of pbov3 and pbov4 have been sequenced, respectively. pbov3 and pbov4 show nucleotide homology to other known bocaviruses in swine and other organisms. open reading frame (orf) analysis has shown that th ... | 2011 | 21605951 |