Publications

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two anti-parvovirus b 19 igm capture assays incorporating a mouse monoclonal antibody specific for b 19 viral capsid proteins vp 1 and vp 2.during an outbreak of parvovirus b 19 in 1989 in northern ireland, 7580 blood donors were screened for b 19 antigen. two units screened positive, one of which was obtained for use as viral antigen. a monoclonal antibody (r92f6) made against this antigen was specific for b 19 capsid proteins vp 1 and vp 2. the monoclonal antibody was used in the development of 2 anti-b 19 igm capture enzyme assays. these used a conventional substrate (o-phenylene diamine) and a chemiluminescent signal reagent. th ...19921550492
an outbreak of parvovirus b19 infection; a study of clinical manifestations and the incidence of fetal loss.eighty-five cases of b19 infection were diagnosed in northern ireland from 1984 to 1989; 65 of these occurred during 1989, the outbreak year. of the total 85 cases, 15 had a rash, 21 had arthralgia, 47 had a rash and arthralgia, and 2 had aplastic crisis. the age range was 4-63 years with a mean of 26.9 years. thirty cases (35%) were referred to hospital; 25 of these had arthralgia and 2 had aplastic crisis. two thousand four hundred pregnant women at 12 weeks gestation in 1989 were screened for ...19948200772
prevalence of disease in dogs purchased from an animal rescue shelter.the prevalence of diseases suffered by dogs within two weeks of their acquisition from a rescue shelter in northern ireland was investigated. a postal questionnaire was completed by 556 people who had purchased a dog from the ulster society for the prevention of cruelty to animals (uspca) to provide information on the diseases suffered by their dog. the majority of the dogs (53.7 per cent) had an ailment the most common being coughing and diarrhoea. of the respondents who returned their dog to t ...199910028582
isolation in cell cultures and initial characterisation of two novel bocavirus species from swine in northern ireland.we report the isolation in cell cultures of two novel bocavirus species in pigs from farms in northern ireland with clinical postweaning multisystemic wasting syndrome (pmws). we have designated the isolates as porcine bocavirus-3 (pbov3) and porcine bocavirus-4 (pbov4). to date 5082 and 4125bps of pbov3 and pbov4 have been sequenced, respectively. pbov3 and pbov4 show nucleotide homology to other known bocaviruses in swine and other organisms. open reading frame (orf) analysis has shown that th ...201121605951
on the trail of a new virus. the calvert lecture 1997. 19989807952
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