| cross-antigenicity among ev71 strains from different genogroups isolated in yamagata, japan, between 1990 and 2007. | we isolated and identified six subgenogroups (b2, b4, b5, c1, c2, and c4) of enterovirus 71 (ev71) between 1990 and 2007 in yamagata, japan. we measured neutralizing antibody (nt ab) titers against those subgenogroup strains and the brcr reference strain for antigenic analysis. serological analysis of 83 residents in yamagata in 2004 showed that differences in the nt ab titer of each individual against the different subgenogroups were mostly within 4-fold. furthermore, sera from guinea pigs, imm ... | 2009 | 19446185 |