| epidemiologic and virologic investigation of hand, foot, and mouth disease, southern vietnam, 2005. | during 2005, 764 children were brought to a large children's hospital in ho chi minh city, vietnam, with a diagnosis of hand, foot, and mouth disease. all enrolled children had specimens (vesicle fluid, stool, throat swab) collected for enterovirus isolation by cell culture. an enterovirus was isolated from 411 (53.8%) of the specimens: 173 (42.1%) isolates were identified as human enterovirus 71 (hev71) and 214 (52.1%) as coxsackievirus a16. of the identified hev71 infections, 51 (29.5%) were c ... | 2007 | 18217559 |
| the seroprevalence and seroincidence of enterovirus71 infection in infants and children in ho chi minh city, viet nam. | enterovirus 71 (ev71)-associated hand, foot and mouth disease has emerged as a serious public health problem in south east asia over the last decade. to better understand the prevalence of ev71 infection, we determined ev71 seroprevalence and seroincidence amongst healthy infants and children in ho chi minh city, viet nam. in a cohort of 200 newborns, 55% of cord blood samples contained ev71 neutralizing antibodies and these decayed to undetectable levels by 6 months of age in 98% of infants. th ... | 2011 | 21765891 |