| immunological relationships of long island isolates of babesia microti. | studies to detect strain differences among two rodent-derived and one human-derived babesia microti isolates from long island were undertaken, using various methods. superinfection experiments using the homologous and heterologous isolates showed cross-protection. all hamsters were resistant to superinfection challenges of increasing dosages of both the homologous and heterologous isolates. attempts to infect other laboratory animals with the long island isolates of b. microti were successful in ... | 1979 | 88904 |
| babesia microti infection in man. | | 1977 | 578184 |
| babesiosis: an underdiagnosed disease of children. | babesiosis is a malaria-like illness caused by the intraerythrocytic parasite babesia microti and is transmitted by the same tick that transmits borrelia burgdorferi, the causative agent of lyme disease. babesiosis is well recognized in adult residents of southern new england and new york but has been described in only five children. to determine whether children are infected with b microti less often than are adults, a prospective serosurvey was carried out on block island, ri, where babesiosis ... | 1992 | 1594345 |
| the prevalence and significance of borrelia burgdorferi in the urine of feral reservoir hosts. | live borrelia burgdorferi were isolated from the blood and/or urine of white-footed mice (peromyscus leucopus) collected on shelter island, new york, in 1984 and 1985. prevalence of spirochetes in urine was consistently higher than in blood or both fluids simultaneously. spirochetes remained viable for 18-24 hours in urine and were maintained in culture for one week. mice removed from the field were spirocheturic for at least 13 months. one spirocheturic mouse developed spirochetemia one month a ... | 1986 | 3577491 |
| human babesiosis. clinical and therapeutic considerations. | during a two-month period, six patients from eastern long island were identified as having babesia microti infection. diagnosis was based on characteristic blood smears, hamster inoculation, or both. symptom duration ranged from 19 to 24 days in five patients. the sixth patient, who had previously undergone splenectomy, had a more severe and prolonged illness. no specific therapy was administered to five patients. the patient who had had a splenectomy was treated with chloroquine, quinine, penta ... | 1982 | 6890585 |
| serosurvey for human babesiosis in new york. | healthy individuals at high risk of exposure to ticks were surveyed to determine the prevalence and incidence of asymptomatic babesiosis on shelter island, new york, during a single transmission season. paired sera obtained in june and october 1978 were tested for antibodies to babesia microti by indirect immunofluorescence. point prevalence values of 4.4% in june and 6.9% in october were obtained. six of 102 persons tested in both months showed at least a fourfold rise in titer of antibodies to ... | 1980 | 7189538 |
| babesiosis in post-splenectomy hosts. | two persons who had been splenectomized later contracted babesiosis, one on cape cod and one near islip, long island, areas where human cases of babesiosis had not been previously identified. one of the patients received pentamidine, but parasitemia persisted after therapy. no deaths have been recorded for persons who had had splenectomies and were later infected with babesia microti. until more effective therapy is available, such patients should be treated conservatively. | 1980 | 7192058 |
| seroprevalence and seroconversion for tick-borne diseases in a high-risk population in the northeast united states. | to determine the prevalence of serologic reactivity, the 1-year incidence of seroconversion, and the frequency of multiple infections, and their associations with symptoms in a group of volunteers at high risk for tick-borne infections in new york state. | 1999 | 10225242 |
| a polymorphic multigene family encoding an immunodominant protein from babesia microti. | human babesiosis in the united states is caused predominantly by babesia microti, a tick-transmitted blood parasite. improved testing methods for the detection of infection with this parasite are needed, since asymptomatic b. microti infection represents a potential threat to the blood supply in areas where b. microti is endemic. we performed immunoscreening of an expression library of genomic dna from a human isolate of b. microti (strain mn1). among 17 unique immunoreactive clones, we identifi ... | 2000 | 10618117 |
| babesia microti, upstate new york. | five cases of human babesiosis were reported in the lower hudson valley region of new york state in 2001. an investigation to determine if babesia microti was present in local ixodes scapularis ticks yielded 5 positive pools in 123 pools tested, the first detection of b. microti from field-collected i. scapularis in upstate new york. | 2005 | 15757571 |
| assessment of polymicrobial infections in ticks in new york state. | ixodes scapularis ticks are clinically important hematophagous vectors. a single tick bite can lead to a polymicrobial infection. we determined the prevalence of polymicrobial infection with borrelia burgdorferi, anaplasma phagocytophilum, babesia microti, borrelia miyamotoi, and powassan virus in 286 adult ticks from the two counties in new york state where lyme disease is endemic, utilizing a masstag multiplex polymerase chain reaction assay. seventy-one percent of the ticks harbored at least ... | 2010 | 19725770 |
| reservoir competence of wildlife host species for babesia microti. | human babesiosis is an increasing health concern in the northeastern united states, where the causal agent, babesia microti, is spread through the bite of infected ixodes scapularis ticks. we sampled 10 mammal and 4 bird species within a vertebrate host community in southeastern new york to quantify reservoir competence (mean percentage of ticks infected by an individual host) using real-time pcr. we found reservoir competence levels >17% in white-footed mice (peromyscus leucopus), raccoons (pro ... | 2012 | 23171673 |
| the prevalence of zoonotic tick-borne pathogens in ixodes scapularis collected in the hudson valley, new york state. | ixodes scapularis, the blacklegged tick, is capable of transmitting the pathogens that cause lyme disease (borrelia burgdorferi), babesiosis (babesia microti), anaplasmosis (anaplasma phagocytophilum), and to a lesser extent powassan encephalitis (deer tick virus [dtv]). these pathogens represent significant public health problems, but little is known about the occurrence and co-infection prevalence of these pathogens in i. scapularis. here, we used standard pcr and pathogen-specific primers to ... | 2014 | 24689680 |
| prevalence of borrelia burgdorferi (spirochaetales: spirochaetaceae), anaplasma phagocytophilum (rickettsiales: anaplasmataceae), and babesia microti (piroplasmida: babesiidae) in ixodes scapularis (acari: ixodidae) collected from recreational lands in the hudson valley region, new york state. | abstract blacklegged ticks, ixodes scapularis say, were collected from 27 sites in eight new york state counties from 2003 to 2006 to determine the prevalence and distribution of tick-borne pathogens in public-use areas over a 4-yr period. in total, 11,204 i. scapularis (3,300 nymphs and 7,904 adults) were individually analyzed using polymerase chain reaction to detect the presence of borrelia burgdorferi (causative agent of lyme disease), anaplasma phagocytophilum (formerly ehrlichia phagocytop ... | 2014 | 24605473 |
| the relevance of forest fragmentation on the incidence of human babesiosis: investigating the landscape epidemiology of an emerging tick-borne disease. | babesiosis is an emerging arthropod-borne infection that has been increasing in incidence for the last decade in the northeastern united states. babesiosis may share features of its landscape epidemiology with other arthropod-borne infections transmitted by the same tick vectors in similar geographic spaces. this study examined 11 years of surveillance data in new york state to measure the relationship between forest fragmentation and the incidence of human babesiosis. adjusted poisson models sh ... | 2013 | 23428092 |