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development of bacterial resistance to the third generation cephalosporins and their clinical use.development of gram-negative rods resistance to the third generation cephalosporins (cefotaxime, ceftazidime, cefoperazone) in connection with their application at the university hospital in olomouc was evaluated in this study. the highest increase in resistance to cefotaxime was detected in enterobacter cloacae (from 22.9% in 1995 to 49.0% in 1997) and enterobacter agglomerans strains (28.0% - 40.5%). in addition, increased resistance to ceftazidime in acinetobacter baumannii (12.5% - 35.1%), e ...199910465127
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