| selective decontamination with nystatin for control of a candida outbreak in a neonatal intensive care unit. | selective decontamination of the digestive tract (sdd) with oral nystatin was evaluated as a measure to control an outbreak of candida infection in a neonatal intensive care unit (nicu). seventy-six out of 106 neonates who carried candida spp. received the main study manoeuvre (the application of oral nystatin in the throat and stomach) during the 12-month open trial. one third of the neonates weighed < 1500 g whilst about half were being ventilated. the mean stay was 33.2 d (sd +/- 46.9). two c ... | 1993 | 8104984 |
| retrospective survey of candidaemia in hospitalized patients and molecular investigation of a suspected outbreak. | episodes of candida infection at a teaching hospital were investigated. during a 3-year period from 1998 to 2000, there were 53 cases of candidaemia. candida albicans (64.2 %) was the most common causative species, followed by candida glabrata (17.0 %) and candida parapsilosis (15.1 %). molecular analysis of a cluster of eight infections from a single unit was performed using southern blotting with ca3 probe hybridization. this showed that the patients were each infected by unrelated strains of ... | 2005 | 15770026 |
| the epidemiology of neonatal and pediatric candidemia in england and wales, 2000-2009. | there are few population-based studies on the epidemiology of neonatal and pediatric invasive candida infections, despite their significant clinical impact on patients. this study aimed to describe the epidemiology of pediatric candidemia in england and wales during a 10-year period as a means of quantifying the changing burden of infection and identifying emerging trends. | 2013 | 23241987 |
| neonatal invasive fungal infection in england 2004-2010. | rates of invasive fungal infection are highest among neonates, especially those of low birthweight. this study aimed to describe the current epidemiology of invasive neonatal fungal infections in a uk neonatal infection surveillance network. from 2004 to 2010 prospective multicentre surveillance was conducted by 14 neonatal units using a web-based database. clinicians then completed a standardized pro forma for each positive fungal blood and/or cerebrospinal fluid culture. the overall incidence ... | 2014 | 24479862 |