| jc virus type 2b is found more frequently in brain tissue of progressive multifocal leukoencephalopathy patients than in urine from controls. | previous studies have shown that strains of human polyomavirus jc (jcv) of asian origin (type 2) are much more highly represented in progressive multifocal leukoencephalopathy (pml) brain than would be expected from their frequency of excretion in urine samples of a comparable control group. the present studies were designed to test whether one subtype of type 2 was preferentially elevated. | 1998 | 10195243 |
| serum antibodies to jc virus, bk virus, simian virus 40, and the risk of incident adult astrocytic brain tumors. | genomic sequences of the human polyomaviruses, jc virus (jcv) and bk virus (bkv), and simian virus 40 (sv40) have been reported from several types of human brain tumors, but there have been no population-based seroepidemiologic studies to evaluate the association between polyomavirus infection and brain tumors. we conducted a case-control study, nested within a prospective cohort, to investigate the association between antibodies to jcv, bkv, and sv40, as measured in serum collected 1-22 years b ... | 2003 | 12750243 |
| cost efficiency in the prospective diagnosis and follow-up of polyomavirus allograft nephropathy. | evaluation of urine cytology (uc) for decoy cells and quantitative determinations of viruria (urine viral load [upcr])and viremia (viral load in blood [vlb]) have been proposed as surrogate markers of polyomavirus allograft nephropathy (pvan). in this study, we present the experience with the concurrent evaluation of uc, upcr, and vlb in 349 patients (940 sets of samples). results were correlated with each other and with a previous, concurrent, or subsequent biopsy diagnosis of pvan. patients we ... | 2004 | 15686687 |
| markers of past infection with simian virus 40 (sv40) and risk of incident non-hodgkin lymphoma in a maryland cohort. | simian virus 40 (sv40) genome sequences have been detected in human non-hodgkin lymphoma (nhl) tissues, and past infection with sv40 may be a risk factor for nhl. we conducted a population-based nested case-control study to investigate the association between serum antibodies to sv40 and incident nhl. two research serum banks were established in washington county, md, with >45,000 volunteers contributing blood samples collected in 1974 and 1989. incident cases of nhl diagnosed through 2002 (n = ... | 2005 | 15941954 |