| mansonella ozzardi in haiti. iv. evaluation of antibody reactivity to heterologous antigens. | sera from individuals in an area of haiti endemic for mansonella ozzardi were analyzed for reactivity to antigens of brugia pahangi, dirofilaria immitis, mansonella llewellyni or ascaris lumbricoides using either an enzyme-linked immunosorbent assay or an indirect immunofluorescent antibody test. igm and igg reactivity to all antigens was observed with sera from both microfilaremic and amicrofilaremic individuals when compared to reactivity of sera from individuals from nonendemic areas. antibod ... | 1986 | 3513647 |
| antifilarial cellular responses detected in a haitian pediatric population by use of a microblastogenesis assay. | previous reports have demonstrated age-related shifts in antifilarial humoral immune responses in 6- to 10-year-old haitian children; the responses consisted of elevated parasite-specific igg2 and igg3 in amicrofilaremic children and elevated igg4 in microfilaremic children. in this study, the cell-mediated immune responses to soluble adult and microfilarial extracts of brugia pahangi, determined by use of a microblastogenesis assay, were examined. capillary blood samples were collected by finge ... | 1991 | 1894942 |
| heightened anti-filarial immune responsiveness in a haitian pediatric population. | the immunological consequences of exposure to filarial infection were examined by cross-sectional serological studies. serum samples from 121 pediatric patients (18 months-15 years of age) were analyzed in parallel with a panel of sera from adults residing in the same area of haiti. parasite antigen specific igg and ige levels were determined by elisa. igg levels in children were significantly elevated in humoral immunoreactivity to brugia pahangi extracts compared to adults. in addition, anti-f ... | 1989 | 2641643 |