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polymorphonuclear cell-mediated vascular injury in anergic surgical patients.we examined the responses of primed polymorphonuclear neutrophils (pmns) adhered to vascular endothelium, which can lead to endothelial cell damage as a mechanism of the capillary leak syndrome, the main cause of death in anergic patients. we tested pmns from (1) preoperative reactive patients, (2) preoperative anergic patients, (3) anergic patients in the surgical intensive care unit, and (4) healthy controls for in vitro adherence and cytotoxicity on cultured human vein endothelial cells. adhe ...19938418783
molecular epidemiology of a vancomycin-intermediate heteroresistant staphylococcus epidermidis outbreak in a neonatal intensive care unit.coagulase-negative staphylococci (cons) have become the leading cause of bloodstream infections (bsis) in intensive care units (icus), particularly in premature neonates. vancomycin-intermediate heteroresistant cons (hvicons) have been identified as sources of bsis worldwide, and their potential to emerge as significant pathogens in the neonatal icu (nicu) remains uncertain. this study describes the molecular epidemiology of an outbreak of vancomycin-heteroresistant (hv) staphylococcus epidermid ...201627401579
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