Publications

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comparative epidemiology of gentamicin-resistant enterobacteria: persistence of carriage and infection.during a two-year period from january 1979, 260 patients have been involved in an outbreak of carriage and infection due to gentamicin-resistant enterobacteria. we have examined the duration of carriage of such enterobacteria and have compared the carriage of klebsiella with that of other resistant enterobacteria. carriage of gentamicin-resistant enterobacteria occurred most frequently and was least sporadic in the intestinal tract. vaginal carriage was observed in 49 out of 68 patients tested a ...19827076872
predominance and genetic diversity of community- and hospital-acquired ctx-m extended-spectrum beta-lactamases in york, uk.this study was conducted to detect the presence of extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae within the faecal flora of both community- and hospital-based patients in york and to characterize the bla(tem), bla(shv) and bla(ctx-m) genes present in these isolates.200415294889
high prevalence of the plasmid-mediated quinolone resistance determinant qnra in multidrug-resistant enterobacteriaceae from blood cultures in liverpool, uk.to determine the prevalence of the plasmid-mediated quinolone resistance qnra gene in a selected collection of blood culture isolates of enterobacteriaceae resistant to both ciprofloxacin and cefotaxime.200516260446
activity of faropenem against cephalosporin-resistant enterobacteriaceae.there is a need for new oral agents active against extended-spectrum beta-lactamase (esbl) producers, as these increasingly cause community-onset infections. we therefore evaluated faropenem, a penem in phase iii development, against recently collected oxyimino-cephalosporin-resistant bacteria.200717353220
a hospital outbreak of extended-spectrum beta-lactamase-producing klebsiella pneumoniae investigated by rapd typing and analysis of the genetics and mechanisms of resistance.between july and september 1997 a ceftazidime- and aminoglycoside-resistant strain of klebsiella pneumoniae infected or colonized seven patients on three paediatric wards at guy's hospital in london. the patients were mostly neonates or infants recovering from cardiac surgery for congenital defects. the organism was probably introduced by an asymptomatic patient from greece and the subsequent outbreak could largely be explained by person-to-person spread on individual wards and frequent transfer ...19989749400
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