| haemorrhagic fever with renal syndrome: clinical, virological and epidemiological perspectives. | haemorrhagic fever with renal syndrome (hfrs) is caused by a group of rna viruses within the family of bunyaviridae known as hantaviruses. the classical, severe form of hfrs is characterized by fever, headache, abdominal and lumbar pain, proteinuria, haemorrhagic phenomena, shock and renal failure. the disease is associated with the prototype hantaan virus and occurs in rural areas of korea and china with apodemus mice as reservoir hosts. a clinically less severe form of hfrs, which is caused by ... | 1987 | 2895603 |
| serological evidence of hantavirus infection in laboratory rats and personnel. | laboratory-acquired haemorrhagic fever with renal syndrome (hfrs) has been reported in many countries. a serological survey of laboratory white rats and of laboratory personnel for antibodies to hantaviruses was conducted in singapore. forty-four per cent (143/329) of rats were seropositive by the indirect immunofluorescent antibody test but none had hantaviral antigens in lung tissues. two of 74 laboratory personnel were seropositive but neither had a history of clinical illness. the high serop ... | 1988 | 2906333 |
| a severe case of hemorrhagic fever with renal syndrome in singapore. | the incidence of human hantavirus infection in singapore is low. hitherto, only 2 cases of hemorrhagic fever with renal syndrome (hfrs) have been reported. a third case is reported here of a ragman who had the classical manifestations of hfrs, confirmed by serology. in addition, his condition was complicated by liver dysfunction and neurological disturbance. after a protracted stay, the patient was finally discharged from hospital 5 months after the onset of his severe illness. | 1996 | 9280013 |