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ecology and prevention of a shellfish-associated hepatitis a epidemic in shanghai, china.during a shellfish-borne hepatitis a outbreak in shanghai during the first quarter of 1988, 300,000 cases were reported in two months. using cell culture and experimental infection of marmosets, hepatitis a virus (hav) was isolated from clams collected from the market and the sea bed during the epidemic. a dose-response curve correlating the quantity of clams consumed to the attack rate of hepatitis a was well documented. the occurrence of the epidemic was associated with a good harvest of clams ...19921335663
an epidemic of hepatitis a attributable to the ingestion of raw clams in shanghai, china.an epidemic of hepatitis a in 1988 in shanghai had an overall attack rate of 4083/100,000 population (292,301 cases). the epidemic curve showed three peaks in january and february. a case-control study of 1208 matched pairs supported that clams were the vehicle for the virus (summary odds ratio, 9.47; p less than .001). analysis of subsets who had eaten clams indicated that only 3.5% with hepatitis a had cooked their clams compared with 18.1% without hepatitis a, and those with the disease consu ...19911658157
epidemiology of hepatitis a and b in the shanghai area: prevalence of serum markers.different population groups from the shanghai area were surveyed by radioimmunoassay for serologic markers of previous infections with hepatitis a virus and hepatitis b virus. there were no significant differences in the prevalence of antibodies to hepatitis a virus (anti-hav) in males and females, or in persons living in rural or urban areas. the prevalence of anti-hav showed a biphasic increase with age, approaching 100% above age 50 years whereas the geometric mean titers declined. the rate o ...19846089547
[a brief account of the 1988 seminar in shanghai on viral hepatitis a]. 19892548683
risk factor analysis of an epidemic of hepatitis a in a factory in shanghai.investigation of an epidemic of hepatitis a which occurred in shanghai in early 1988 was conducted at the shanghai no. 2 yarn dyeing and weaving mill. in this factory the attack rate between january and april 1988 was 9%. the rate was highest among staff who ate raw clams (18%) and higher among those who ate cooked clams (7%) than among those who did not eat clams (2%). in addition, independent risk factors for infection were: age below 30 years (relative risk (rr) = 3.0, 95% cl: 2.0, 4.5) shift ...19902165466
a serologically confirmed, case-control study, of a large outbreak of hepatitis a in china, associated with consumption of clams.a matched and serologically confirmed case-control study was carried out to investigate the source of an outbreak of acute hepatitis involving 290,000 cases in the suburbs of shanghai, in january 1988. a total of 132 patients with acute hepatitis from six different hospitals were chosen as cases and the same number of control patients without hepatitis were matched for gender, age, admission date and area of residence. serum specimens from both case and control patients were detected for specifi ...19911661240
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